Hartman Rachael, Mandal Rajni, Sanchez Miguel, Stein Jennifer A
Department of Dermatology, New York University, New York, NY, USA.
Dermatol Online J. 2010 Nov 15;16(11):22.
We describe a 73-year-old woman with a long-standing history of annular, hyperkeratotic papules that began on the palms and soles and gradually spread to her trunk, extremities, and face. The clinical presentation and biopsy findings were consistent with PPPD, which is a rare subtype of porokeratosis that begins on the palms and soles and gradually spreads to the trunk and extremities. Owing to the risk of malignant degeneration in porokeratosis, patients should be closely monitored with total body skin examinations. There is no definitive treatment for PPPD. Oral retinoids are sometimes helpful although relapses are common after discontinuation of therapy.
我们描述了一位73岁女性，她有长期的环形、角化过度丘疹病史，最初出现在手掌和脚底，随后逐渐蔓延至躯干、四肢和面部。临床表现和活检结果与掌跖播散性浅表性光化性汗孔角化症（PPPD）相符，PPPD是汗孔角化症的一种罕见亚型，始于手掌和脚底，逐渐蔓延至躯干和四肢。由于汗孔角化症存在恶变风险，患者应通过全身皮肤检查进行密切监测。PPPD尚无确切的治疗方法。口服维甲酸有时会有帮助，尽管停药后复发很常见。
