Applied Physics Laboratory, Johns Hopkins University, Laurel, MD 20723-6099, USA.
Ultrasonics. 2011 May;51(4):467-71. doi: 10.1016/j.ultras.2010.11.012. Epub 2010 Nov 27.
Attenuation estimation and imaging in the cervix has been utilized to evaluate the onset of cervical ripening during pregnancy. This feature has also been utilized for the acoustic characterization of leiomyomas and myometrial tissue. In this paper, we present direct narrowband substitution measurement values of the variation in the ultrasonic attenuation coefficient in ex vivo human uterine and cervical tissue, in the 5-10 MHz frequency range. At 5 MHz, the attenuation coefficient values are similar for the different orientations of uterine tissue with values of 4.1-4.2 dB/cm, 5.1 dB/cm for the leiomyoma, and 6.3 dB/cm for the cervix. As the frequency increases, the attenuation coefficient values increase and are also spread out, with a value of approximately 12.6 dB/cm for the uterus (both parallel and perpendicular), 16.0 for the leiomyoma, and 26.8 dB/cm for the cervix at 10 MHz. The attenuation coefficient measured increases monotonically over the frequency range measured following a power law.
在怀孕期间,已经利用宫颈的衰减估计和成像来评估宫颈成熟的开始。这项功能还可用于子宫肌瘤和子宫组织的声学特征描述。在本文中,我们展示了在 5-10MHz 频率范围内,离体人子宫和宫颈组织中超声衰减系数变化的直接窄带替代测量值。在 5MHz 时,子宫组织的不同取向的衰减系数值相似,为 4.1-4.2dB/cm,子宫肌瘤为 5.1dB/cm,宫颈为 6.3dB/cm。随着频率的增加,衰减系数值增加并且分布更广泛,子宫(平行和垂直)的约为 12.6dB/cm,子宫肌瘤为 16.0dB/cm,宫颈为 10MHz 时为 26.8dB/cm。在所测量的频率范围内,测量的衰减系数值遵循幂律单调增加。