Song Ning-Hong, Wu Hong-Fei, Xu Nai-Cen, Yang Jie
Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
J Androl. 2012 Jan-Feb;33(1):45-9. doi: 10.2164/jandrol.110.012153. Epub 2010 Dec 16.
Our objective was to comprehensively test the composition, morphology, and structure of enlarged prostatic utricle (EPU) stones, which, as a kind of biolite in abnormal anatomical structures of the genitourinary system, have not yet been reported. Thirty-one EPU stones coming from 8 patients, who had been treated in our center from 1985 to 2009, were taken out by transurethral fenestration of EPU and were analyzed by scanning electron microscopy, x-ray diffraction (XRD) analysis, and Fourier transformation infrared spectral (FTIS) analysis. Under scanning electron microscope, all these EPU calculi were seen to be constituted of many intensive minicrystals and amorphous matrix. By XRD and FTIS analysis, we determined that the 31 EPU stones in our research were all hydroxyapatite crystal. We consider that EPU calculi should belong to the category of prostatic pseudocalculi and that the formation of EPU calculi is not caused by the abnormal change of urine composition, but should be ascribed to continuously concentrated EPU liquid by absorption of capsule walls and calculous matrix mainly coming from deciduous epithelial cells of EPUs. The role of the amorphous matrix is to link microcrystals, which promotes the growth of EPU stones.
我们的目的是全面检测前列腺囊扩大（EPU）结石的成分、形态和结构，作为泌尿生殖系统异常解剖结构中的一种生物结石，此前尚无相关报道。从1985年至2009年在我们中心接受治疗的8例患者中取出31颗EPU结石，通过经尿道前列腺囊开窗术取出，并进行扫描电子显微镜、X射线衍射（XRD）分析和傅里叶变换红外光谱（FTIS）分析。在扫描电子显微镜下，所有这些EPU结石均由许多密集的微晶和无定形基质构成。通过XRD和FTIS分析，我们确定本研究中的31颗EPU结石均为羟基磷灰石晶体。我们认为EPU结石应属于前列腺假结石范畴，EPU结石的形成并非由尿液成分异常变化所致，而应归因于囊壁和结石基质（主要来自EPU的脱落上皮细胞）吸收导致EPU液持续浓缩。无定形基质的作用是连接微晶，从而促进EPU结石的生长。
