MRC/UVRI Uganda Research Unit on AIDS, Uganda Virus Research Institute, Entebbe, Uganda.
Pediatr Infect Dis J. 2011 Jun;30(6):535-7. doi: 10.1097/INF.0b013e3182076864.
Hypersensitivity reactions are reported in approximately 5% of adults receiving abacavir, but there are few published data in children. Among 1150 African children receiving antiretroviral therapy in a randomized trial, suspected hypersensitivity reactions to abacavir were rare (0.3%; 95% CI, 0.01-0.9). Patients were managed successfully through the provision of clear guidelines and education of clinical staff, children, and their caregivers.
约有 5%接受阿巴卡韦治疗的成年人会出现超敏反应，但在儿童中发表的数据很少。在一项随机试验中，1150 名接受抗逆转录病毒治疗的非洲儿童中，疑似阿巴卡韦超敏反应罕见（0.3%；95%CI，0.01-0.9）。通过提供明确的指南和对临床工作人员、儿童及其照顾者进行教育，成功地管理了这些患者。
