Berg Ansgar, Furu Kari, Einen Margrete, Spigset Olav
Kompetansesenteret for klinisk forskning, Klinisk forskningspost – barn, Haukeland universitetssykehus, 5021 Bergen, Norway.
Tidsskr Nor Laegeforen. 2010 Dec 16;130(24):2474-5. doi: 10.4045/tidsskr.10.0503.
Lower respiratory tract infections are common in small children, and are often associated with obstruction of the respiratory tract and coughing. In Norway, symptomatic treatment with ephedrine is common in children. The clinical effect of such treatment is not sufficiently documented and serious adverse drug reactions have been reported in small children administered sympathomimetic medication. This article presents current knowledge of clinical effects and adverse drug reactions of ephedrine in infants and children, and discusses the practical implications of these findings.
下呼吸道感染在幼儿中很常见,并且常常与呼吸道阻塞和咳嗽有关。在挪威,用麻黄碱进行对症治疗在儿童中很普遍。这种治疗的临床效果尚无充分记录,而且在给予拟交感神经药物的幼儿中已报告有严重的药物不良反应。本文介绍了麻黄碱在婴幼儿中的临床效果和药物不良反应的现有知识,并讨论了这些发现的实际意义。