Lim Soo Hyun, Jeong Byong Chang, Seo Seong Il, Jeon Seong Soo, Han Deok Hyun
Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean J Urol. 2010 Nov;51(11):777-82. doi: 10.4111/kju.2010.51.11.777. Epub 2010 Nov 17.
The aim of this study was to evaluate the efficacy and safety of retrograde intrarenal surgery (RIRS) for the treatment of renal stones and to analyze the predictive factors for stone-free.
We retrospectively reviewed the records of patients who underwent RIRS for renal stones from January 2000 to July 2009. We identified 66 RIRSs (63 patients with 3 bilateral renal stones) and collected data. Stone-free and success were respectively defined as no visible stones and clinically insignificant residual stones less than 3 mm on postoperative imaging; predictive factors for stone-free were evaluated.
Of the 66 renal stones, 18 stones (27.3%) were located in the upper pole or midpole or renal pelvis and 48 (72.7%) in the lower pole with or without others, respectively. The mean cumulative stone burden was 168.9±392.5 mm(2). The immediate postoperative stone-free rate was 69.7%, and it increased to 72.7% at 1 month after surgery. The success rate was 80.3% both immediately after the operation and 1 month later. In the multivariate analysis, stone location except at the lower pole (p=0.049) and small cumulative stone burden (p=0.002) were significantly favorable predictive factors for the immediate postoperative stone-free rate. The overall complication rate was 6%.
RIRS is a safe and effective treatment for renal stones. The stone-free rate of RIRS was particularly high for renal stones with a small burden, except for those located in the lower pole. RIRS could be considered in selective patients with renal stones.
本研究旨在评估逆行性肾内手术(RIRS)治疗肾结石的疗效和安全性,并分析结石清除的预测因素。
我们回顾性分析了2000年1月至2009年7月期间接受RIRS治疗肾结石的患者记录。我们确定了66例RIRS手术(63例患者,其中3例为双侧肾结石)并收集了数据。结石清除定义为术后影像学检查无可见结石且残留结石小于3mm且临床意义不显著;评估结石清除的预测因素。
66例肾结石中,18例(27.3%)位于上极或中极或肾盂,48例(72.7%)位于下极,分别伴有或不伴有其他部位结石。平均累积结石负荷为168.9±392.5mm²。术后即刻结石清除率为69.7%,术后1个月升至72.7%。术后即刻及术后1个月成功率均为80.3%。多因素分析显示,除下极外的结石位置(p=0.049)和较小的累积结石负荷(p=0.002)是术后即刻结石清除率的显著有利预测因素。总体并发症发生率为6%。
RIRS是治疗肾结石的一种安全有效的方法。对于负荷较小的肾结石,RIRS的结石清除率特别高,但位于下极的结石除外。对于选择性肾结石患者可考虑采用RIRS。