Matthaei M, Steinberg J, Wiermann A, Richard G, Klemm M
Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Ophthalmologe. 2011 Jul;108(7):637-43. doi: 10.1007/s00347-010-2305-6.
Canaloplasty provides a new option in non-penetrating glaucoma surgery. The aim of this study is to examine its early postsurgical safety and efficacy.
This was a retrospective study of canaloplasties performed at our institution in 2009 (n=46, 13 of which were combined with cataract surgery). The mean follow-up was 6.0±3.4 months. The most important parameters examined were intraocular pressure (IOP), number of topical medications, postoperative complications, and required additional surgery.
Mean presurgical IOP: 18.2±5.8 mmHg on a mean of 2.3±1.2 applied topical medications. Mean postsurgical IOP: 12.3±5.1 mmHg at 3 months, 11.7±3.0 mmHg at 6 months, and 12.6±2.4 mmHg at 12 months. Number of postsurgical medications: 0.8±1.1 at 3 months, 1.2±1.3 at 6 months, and 1.0±1.1 at 12 months. The most frequent postoperative complications were transient hypotension (32.6%), bleb leakage (26.1%), and microhyphema (23.9%). Revision surgery was required in 8.7% of all patients.
Canaloplasty showed a good IOP-reducing effect. Complications occurred mostly temporarily and were of a controllable nature.
房角成形术为非穿透性青光眼手术提供了一种新选择。本研究旨在探讨其术后早期的安全性和有效性。
这是一项对2009年在我们机构进行的房角成形术的回顾性研究（n = 46，其中13例联合白内障手术）。平均随访时间为6.0±3.4个月。所检查的最重要参数为眼压（IOP）、局部用药数量、术后并发症以及所需的额外手术。
术前平均眼压：在平均使用2.3±1.2种局部用药时为18.2±5.8 mmHg。术后平均眼压：3个月时为12.3±5.1 mmHg，6个月时为11.7±3.0 mmHg，12个月时为12.6±2.4 mmHg。术后用药数量：3个月时为0.8±1.1种，6个月时为1.2±1.3种，12个月时为1.0±1.1种。最常见的术后并发症为短暂性低血压（32.6%）、滤过泡渗漏（26.1%）和微小前房积血（23.9%）。所有患者中有8.7%需要进行翻修手术。
房角成形术显示出良好的降眼压效果。并发症大多为暂时性，且具有可控性。
