Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA.
J Autism Dev Disord. 2011 Oct;41(10):1352-61. doi: 10.1007/s10803-010-1161-1.
Autism spectrum disorder (ASD) often involves sensory and motor problems, yet the proprioceptive sense of limb position has not been directly assessed. We used three tasks to assess proprioception in adolescents with ASD who had motor and sensory perceptual abnormalities, and compared them to age- and IQ-matched controls. Results showed no group differences in proprioceptive accuracy or precision during active or passive tasks. Both groups showed (a) biases in elbow angle accuracy that varied with joint position, (b) improved elbow angle precision for active versus passive tasks, and (c) improved precision for a fingertip versus elbow angle estimation task. Thus, a primary proprioceptive deficit may not contribute to sensorimotor deficits in ASD. Abnormalities may arise at later sensory processing stages.
自闭症谱系障碍（ASD）常伴有感觉和运动问题，但肢体位置本体感觉尚未被直接评估。我们使用三种任务来评估患有运动和感觉知觉异常的 ASD 青少年的本体感觉，并将其与年龄和智商匹配的对照组进行比较。结果显示，在主动或被动任务中，两组在本体感觉准确性或精密度方面均无差异。两组都表现出：（a）关节位置变化导致的肘部角度准确性偏差；（b）主动任务与被动任务相比，肘部角度精密度提高；（c）指尖与肘部角度估计任务相比，精密度提高。因此，主要本体感觉缺陷可能不会导致 ASD 中的感觉运动缺陷。异常可能出现在较晚的感觉处理阶段。
