Pitts P, Fenwick B, Fromberg B
Prog Cardiovasc Nurs. 1990 Apr-Jun;5(2):65-72.
The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Trial was a multicenter, randomized trial designed with the purpose of determining the clinical impact of immediate or deferred angioplasty on left ventricular function following successful myocardial reperfusion with tissue plasminogen activator (t-PA). Results from this trial indicate that immediate coronary angioplasty following successful thrombolysis, when coronary artery anatomy is suitable, offers no advantage over delayed elective angioplasty. The purpose of this article is to discuss and critically review the TAMI trial. Details of the trial will be discussed followed by a critique and implications for nursing.
心肌梗死溶栓与血管成形术(TAMI)试验是一项多中心随机试验,旨在确定在成功使用组织纤溶酶原激活剂(t-PA)实现心肌再灌注后,立即或延迟进行血管成形术对左心室功能的临床影响。该试验结果表明,在冠状动脉解剖结构合适时,溶栓成功后立即进行冠状动脉血管成形术相比延迟选择性血管成形术并无优势。本文旨在讨论并严格审视TAMI试验。将先讨论试验细节,随后进行评论并阐述其对护理工作的启示。