干扰素对抗体形成的影响。
Effect of interferon on antibody formation.
作者信息
Johnson H M
出版信息
Tex Rep Biol Med. 1977;35:357-69.
PMID:211665
Abstract
Virus-type interferon is capable of suppressing the antibody response both in vivo and in vitro. Interferon induced by antigen or mitogen (immune interferon) primarily in T lymphocytes also appears capable of suppressing the antibody response. Cyclic AMP has a regulatory effect on the induction of both virus-type and immune interferon. The immunosuppressive effects of virus-type and immune interferon may differ at the cellular or subcellular level.
摘要
病毒型干扰素在体内和体外均能抑制抗体反应。主要由T淋巴细胞中的抗原或有丝分裂原诱导产生的干扰素（免疫干扰素）似乎也能够抑制抗体反应。环磷酸腺苷对病毒型干扰素和免疫干扰素的诱导均有调节作用。病毒型干扰素和免疫干扰素的免疫抑制作用在细胞或亚细胞水平上可能有所不同。
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