Abubakar M, Arshed M Javed, Hussain M, Ali Q
National Veterinary Laboratory, Islamabad, Pakistan.
National Veterinary Laboratory, Islamabad, Pakistan Faculty of Veterinary and Animal Sciences, PMAS-Arid Agriculture University, Rawalpindi, Pakistan.
Transbound Emerg Dis. 2011 Apr;58(2):152-6. doi: 10.1111/j.1865-1682.2010.01193.x. Epub 2010 Dec 20.
The following is the first detailed description of laboratory confirmed evidence of peste des petits ruminant virus (PPRV) in 14 districts of Sindh province, Pakistan. Sindh is the 2nd largest province of Pakistan in terms of human population and livestock. Livestock are the main origin of the people's livelihood. Samples were collected during the surveillance programme from sheep and goats showing severe respiratory signs and mouth lesions. Competitive enzyme-linked immuno-sorbant assay (cELISA) was performed to detect the presence of antibodies in the serum against PPRV. Findings suggested that the overall PPR sero-prevalence in sheep was 49.5% when compared to goats, which was 56.3%. As we observed during an 18 months' period, most of the cases that occurred emerged with the start of hot season and peaked during the months of April, May, June and July, and then the prevalence dropped. Among various age groups, the animals that showed the higher prevalence of antibodies to PPRV were >2 years. In the age group <1 year, there was a significant difference in the prevalence which was 48.6% in goats when compared to 32.1% in sheep. Similarly, it was the same in the second age group (1-2 years), 46.9% in sheep when compared to 55.3% goats. There was little variation in the third age group (>2 years), being around 61.7% in goats when compared to 63.4% in sheep. The highest sero-prevalence was in Tharparkar followed by Mirpur Khas and Tando Allahyar. The study indicated the scenario of PPRV circulation in the population of the two domestic ruminant species (sheep and goats) with frequent disease outbreaks.
以下是对巴基斯坦信德省14个地区小反刍兽疫病毒（PPRV）实验室确诊证据的首次详细描述。信德省是巴基斯坦人口和牲畜数量第二大的省份。牲畜是当地人民生计的主要来源。在监测项目期间，从出现严重呼吸道症状和口腔病变的绵羊和山羊身上采集了样本。采用竞争酶联免疫吸附测定（cELISA）检测血清中抗PPRV抗体的存在。研究结果表明，与山羊的56.3%相比，绵羊的总体PPR血清阳性率为49.5%。在我们观察的18个月期间，大多数病例在炎热季节开始时出现，并在4月、5月、6月和7月达到高峰，然后患病率下降。在各个年龄组中，抗PPRV抗体患病率较高的动物是年龄大于2岁的。在年龄小于1岁的组中，患病率存在显著差异，山羊为48.6%，而绵羊为32.1%。同样，在第二个年龄组（1 - 2岁）中也是如此，绵羊为46.9%，而山羊为55.3%。在第三个年龄组（大于2岁）中差异不大，山羊约为61.7%，而绵羊为63.4%。血清阳性率最高的是塔尔帕卡尔，其次是米尔布尔哈斯和坦多阿拉亚尔。该研究表明了PPRV在两种家养反刍动物（绵羊和山羊）群体中传播且疾病频繁爆发的情况。
