以单纯疱疹病毒脑炎为表现的普通变异型免疫缺陷病。
Common variable immunodeficiency presenting as herpes simplex virus encephalitis.
出版信息
J Allergy Clin Immunol. 2011 Feb;127(2):541-3. doi: 10.1016/j.jaci.2010.11.004. Epub 2010 Dec 16.
Abstract
Common variable immunodeficiency (CVID) is a disorder in which patients are unusually susceptible to infections with encapsulated bacteria. Here we describe three adults with CVID in whom the correct diagnosis was not reached until they had Herpes simplex encephalitis. Failure to identify the underlying immune deficiency likely contributed to these debilitating infections.
摘要
普通变异性免疫缺陷症（CVID）是一种患者对带囊膜细菌感染异常敏感的疾病。我们在此描述了 3 例成人 CVID 患者，直到他们患上单纯疱疹性脑炎，才得到正确诊断。未能识别潜在的免疫缺陷可能导致了这些使人衰弱的感染。
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本文引用的文献
1
Late-onset combined immune deficiency: a subset of common variable immunodeficiency with severe T cell defect.迟发性联合免疫缺陷：一种伴有严重T细胞缺陷的常见可变免疫缺陷亚型。
Clin Infect Dis. 2009 Nov 1;49(9):1329-38. doi: 10.1086/606059.
2
TLR3 deficiency in patients with herpes simplex encephalitis.单纯疱疹性脑炎患者的Toll样受体3缺陷
Science. 2007 Sep 14;317(5844):1522-7. doi: 10.1126/science.1139522.
3
Herpes simplex virus encephalitis in human UNC-93B deficiency.人类UNC-93B缺陷型单纯疱疹病毒性脑炎。
Science. 2006 Oct 13;314(5797):308-12. doi: 10.1126/science.1128346. Epub 2006 Sep 14.
4
TLR9 activation is defective in common variable immune deficiency.Toll样受体9（TLR9）激活在常见变异型免疫缺陷中存在缺陷。
J Immunol. 2006 Feb 1;176(3):1978-87. doi: 10.4049/jimmunol.176.3.1978.
5
Practice parameter for the diagnosis and management of primary immunodeficiency.原发性免疫缺陷诊断与管理的实践参数
Ann Allergy Asthma Immunol. 2005 May;94(5 Suppl 1):S1-63. doi: 10.1016/s1081-1206(10)61142-8.
6
B cell-deficient mice have increased susceptibility to HSV-1 encephalomyelitis and mortality.
J Neuroimmunol. 1999 Feb 1;94(1-2):122-6. doi: 10.1016/s0165-5728(98)00238-0.
7
Use of monoclonal antibody directed against herpes simplex virus glycoproteins to protect mice against acute virus-induced neurological disease.使用针对单纯疱疹病毒糖蛋白的单克隆抗体来保护小鼠免受急性病毒诱导的神经疾病。
Infect Immun. 1981 Oct;34(1):192-9. doi: 10.1128/iai.34.1.192-199.1981.
8
Murine hepatitis virus-4 (strain JHM)-induced neurologic disease is modulated in vivo by monoclonal antibody.鼠肝炎病毒4型（JHM株）诱导的神经疾病在体内受到单克隆抗体的调节。
Virology. 1984 Jan 30;132(2):261-70. doi: 10.1016/0042-6822(84)90033-3.
9
Herpes simplex virus type 1 infection in mice with severe combined immunodeficiency (SCID).1型单纯疱疹病毒在严重联合免疫缺陷（SCID）小鼠中的感染。
Arch Virol. 1988;103(1-2):73-82. doi: 10.1007/BF01319810.
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