Nyström Alf, Lundqvist Kristina, Sjöstrand Johan
Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation University of Gothenburg, Mölndal, Sweden.
J AAPOS. 2010 Dec;14(6):522-6. doi: 10.1016/j.jaapos.2010.09.018.
To characterize the longitudinal changes of refraction in aphakic eyes after early surgery for congenital cataract and to evaluate longitudinally measured aphakic refraction (individual vs group mean) as a noninvasive indicator of postoperative disturbances in ocular development.
Records of children who had cataract surgery during their first year of life between 1980 and 1995 were obtained from a prospective, population-based study of congenital cataract. Only children with regular follow-up were included. Postoperative aphakic refraction was calculated at the corneal plane. Data were obtained up to 36 months of age.
The study included 28 children (49 eyes) who underwent surgery at a median age of 2.8 months (range, 0-9 months). The decrease of aphakic refraction at the corneal plane followed a logarithmic trend (R(2) = 0.95). A total of 36 eyes followed this pattern, with no growth in 8 eyes and an increased growth rate in 1 eye with uncontrolled glaucoma and 4 eyes of 2 children with Down syndrome.
Most aphakic eyes follow a predictable, logarithmic change in refraction in the first 3 years of life, Longitudinal monitoring of refraction may prove to be a useful, noninvasive screening method for early detection of disturbances in aphakic eye growth.
描述先天性白内障早期手术后无晶状体眼屈光的纵向变化，并纵向评估无晶状体眼屈光（个体与群体平均值）作为眼发育术后紊乱的非侵入性指标。
从一项基于人群的先天性白内障前瞻性研究中获取1980年至1995年期间在出生后第一年接受白内障手术的儿童的记录。仅纳入有定期随访的儿童。在角膜平面计算术后无晶状体眼屈光。获取的数据截至36月龄。
该研究纳入了28名儿童（49只眼），他们接受手术的中位年龄为2.8个月（范围0 - 9个月）。角膜平面无晶状体眼屈光的降低呈对数趋势（R² = 0.95）。共有36只眼遵循此模式，8只眼无增长，1只患有未控制青光眼的眼以及2名唐氏综合征儿童的4只眼增长速率增加。
大多数无晶状体眼在生命的前3年屈光遵循可预测的对数变化，屈光的纵向监测可能被证明是一种用于早期检测无晶状体眼生长紊乱的有用的非侵入性筛查方法。
