Department of Psychiatry, Palacky University Olomouc, I. P. Pavlova 6, Olomouc, Czech Republic.
Psychiatr Danub. 2010 Dec;22(4):528-34.
Bipolar disorders are often associated with cognitive deficits, which have an influence on social functioning and the course of the illness. These deficits have an impact on occupational ability and social integration.
To ascertain cognitive function, level of dissociation and quality of life and their interrelations in patients with bipolar affective disorder in remission. Data from D2 Attention Test, Verbal Fluency Test and Trial Making Test, Dissociative Experiences Scale (DES). Quality of Life Satisfaction and Enjoyment (Q-LES-Q) and M.I.N.I. (MINI-international neuropsychiatric interview were statistically analyzed.
There are no significant correlations between applied cognitive tests and dissociation scale DES. There are no significant correlations between applied cognitive tests and dissociation scale DES. There were no differences between employed and unemployed patients in DES, pathological DES and in any of Q-.LES-Q domains.
We need further research to explore the role of cognitive functions and dissociation in bipolar affective disorder and its relationship to cognitive functions, emotional regulation, biological factors and therapy outcome.
双相情感障碍常伴有认知缺陷，认知缺陷会影响社会功能和疾病进程。这些缺陷会影响职业能力和社会融合。
为了确定缓解期双相情感障碍患者的认知功能、分离程度和生活质量及其相互关系。使用 D2 注意力测验、词语流畅性测验和连线测验，以及分离体验量表（DES）来评估数据。采用生活质量满意度和享受量表（Q-LES-Q）和 MINI 国际神经精神访谈（MINI-international neuropsychiatric interview）进行统计分析。
应用认知测试与分离量表 DES 之间无显著相关性。DES、病理性 DES 以及 Q-LES-Q 任何领域的得分在就业和失业患者之间均无差异。
我们需要进一步的研究来探索认知功能和分离在双相情感障碍中的作用及其与认知功能、情绪调节、生物因素和治疗结果的关系。
