Gipson C L, Johnson G A, Fisher R, Stewart A, Giles G, Johnson J O, Tobias J D
Department of Anesthesiology, University of Missouri, Columbia, Missouri.
J Minim Access Surg. 2006 Jun;2(2):67-72. doi: 10.4103/0972-9941.26651.
Changes in cardiac output may occur during insufflation for laparoscopic procedures. However, there are limited data regarding its potential effects on cerebral oxygenation.
Cerebral oxygenation (ScO(2)), end tidal CO(2), heart rate, blood pressure and oxygen saturation by pulse oximetry were recorded every 5 minutes prior to insufflation, during insufflation and after desufflation. Minute ventilation was increased to maintain normocapnia and the depth of anesthesia was adjusted or fluids/phenylephrine administered to maintain the blood pressure within 20% of the baseline.
The cohort for the study included 70 adults for laparoscopic herniorrhaphy, gastric bypass or cholecystectomy. A total of 1004 ScO(2) values were obtained during laparoscopy. The ScO(2) decreased from the baseline in 758 of the 1004 data points. The ScO(2) was 0-9 less than the baseline in 47.8% of the values, 10-19 less than the baseline in 24.9% of the values and 20-29 less than the baseline in 26 values (2.6%). Eighty-two (8.2%) of the values were less than 80% of the baseline value, while 25 values (2.5%) were less than 75% of the baseline value. Twelve patients had at least one ScO(2) value that was less than 80% of the baseline and 6 had at least one ScO(2) value that was less than 75% of the baseline. Four patients of the cohort had ScO(2) values less than 80% of the baseline for more than 50% of the laparoscopic procedure.
Although relatively uncommon, significant changes in cerebral oxygenation do occur in some patients during insufflation for laparoscopic surgery.
腹腔镜手术气腹过程中心输出量可能发生变化。然而,关于其对脑氧合潜在影响的数据有限。
在气腹前、气腹期间和放气后,每隔5分钟记录脑氧合(ScO₂)、呼气末二氧化碳分压、心率、血压和脉搏血氧饱和度。增加分钟通气量以维持正常碳酸血症,并调整麻醉深度或给予液体/去氧肾上腺素以将血压维持在基线的20%以内。
该研究队列包括70例接受腹腔镜疝修补术、胃旁路手术或胆囊切除术的成年人。腹腔镜检查期间共获得1004个ScO₂值。在1004个数据点中,有758个ScO₂值较基线下降。47.8%的值比基线低0 - 9,24.9%的值比基线低10 - 19,26个值(2.6%)比基线低20 - 29。82个(8.2%)值低于基线值的80%,而25个值(2.5%)低于基线值的75%。12例患者至少有一个ScO₂值低于基线值的80%,6例患者至少有一个ScO₂值低于基线值的75%。该队列中有4例患者在超过50%的腹腔镜手术过程中ScO₂值低于基线值的80%。
尽管相对不常见,但在腹腔镜手术气腹期间,一些患者确实会出现显著的脑氧合变化。