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维生素与肺癌

Vitamins and lung cancer.

作者信息

Stam J, Strankinga W F, Fikkert J J, Schrijver J, Hulshof K

机构信息

Academic Hospital, Free University, Dept. of Pulmonology, Amsterdam, The Netherlands.

出版信息

Lung. 1990;168 Suppl:1075-81. doi: 10.1007/BF02718246.

Abstract

Several factors are known to promote the development of a lung cancer. Smoking, occupation, environment, chronic bronchitis, and scars in the lung are all risk factors. Many studies have stressed the importance of nutrition, in particular vitamins. Vitamin A is necessary for cell differentiation. Retrospective and prospective studies have proven the inverse relation between provitamin A, beta-carotene, and lung cancer of the squamous and oat cell types. Studies in which beta-carotene or natural vitamin A are supplied to smokers, controls, and patients after resection for lung cancer are in progress. The study of other vitamins such as vitamin C and vitamin E has not led to definitive conclusions. The trace element selenium may also exert a beneficial effect.

摘要

已知有几个因素会促进肺癌的发展。吸烟、职业、环境、慢性支气管炎和肺部瘢痕都是危险因素。许多研究都强调了营养的重要性,尤其是维生素。维生素A对细胞分化是必需的。回顾性和前瞻性研究已经证实了维生素原A、β-胡萝卜素与鳞状细胞癌和燕麦细胞癌之间的反比关系。向吸烟者、对照组以及肺癌切除术后的患者补充β-胡萝卜素或天然维生素A的研究正在进行中。对其他维生素如维生素C和维生素E的研究尚未得出明确结论。微量元素硒也可能发挥有益作用。

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