Matschke Jakob
Forensic Neuropathology Unit, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Am J Forensic Med Pathol. 2010 Dec;31(4):364-9. doi: 10.1097/paf.0b013e3181fbe45a.
Sudden unexpected death is any nontraumatic death in healthy individuals with normal activities for age until acute demise. Whereas not uncommon in adults and infants, it is considered a rarity in children, with most cases due to infection or occult cardiovascular abnormalities. Pathologic intracranial findings are rarely found in sudden unexpected death in childhood, with most cases due to occult intracranial neoplasms. Cerebral arterial dissection is an uncommon cause of arterial ischemic stroke in childhood. Outcome is poor, with more than 20% of patients dying. We report 4 cases of sudden unexpected death due to arterial ischemic stroke after cerebral arterial dissection in childhood and present a review of the literature.
猝死是指健康个体在日常正常活动中直至急性死亡时发生的非创伤性死亡。虽然在成人和婴儿中并不罕见，但在儿童中被认为是罕见的，大多数病例是由于感染或隐匿性心血管异常。在儿童猝死中很少发现病理性颅内病变，大多数病例是由于隐匿性颅内肿瘤。脑动脉夹层是儿童动脉缺血性卒中的罕见病因。预后较差，超过20%的患者死亡。我们报告4例儿童脑动脉夹层后因动脉缺血性卒中导致的猝死病例并对文献进行综述。
