Alotaibi Azizah S, Mahroos Rabya A, Al Yateem Samia S, Menezes Ritesh G
College of Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Department of Pathology, College of Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Cureus. 2022 Jan 4;14(1):e20944. doi: 10.7759/cureus.20944. eCollection 2022 Jan.
Sudden unexpected death due to central nervous system (CNS)-related pathologies though far less common than cardiac causes still account for a substantial proportion of sudden deaths that occur worldwide. This review covers the most common causes of sudden unexpected death due to CNS-related pathologies encountered by forensic pathologists. These include intracerebral hemorrhage, aneurysmal subarachnoid hemorrhage, ischemic stroke, epilepsy, brain tumors, and infectious causes. Related rare causes are not discussed and are beyond the scope of this review. The role of neuroimaging and genetic testing as autopsy ancillary investigations in such sudden deaths is also discussed.
虽然中枢神经系统（CNS）相关病变导致的意外猝死远不如心脏原因常见，但在全球范围内发生的猝死中仍占相当大的比例。本综述涵盖了法医病理学家遇到的中枢神经系统相关病变导致意外猝死的最常见原因。这些原因包括脑出血、动脉瘤性蛛网膜下腔出血、缺血性中风、癫痫、脑肿瘤和感染性病因。相关罕见原因不在本文讨论范围内，超出了本综述的范畴。本文还讨论了神经影像学和基因检测在这类猝死尸检辅助检查中的作用。
