Wybran J, Libin M, Schandene L
Department of Immunology, Hematology, and Transfusion, Hôpital Erasme, Université Libre de Bruxelles, Belgium.
Lung. 1990;168 Suppl:720-5. doi: 10.1007/BF02718199.
The influence of Broncho-Vaxom (BV) on different immune parameters was investigated in vitro on human peripheral blood mononuclear cells (PBMC). It was found that BV enhances the natural killer (NK) activity of PBMC and increases their spontaneous and phytohemagglutin (PHA)-induced production of tumor-necrosis factor--alpha and interleukin-2 as well as the PHA-stimulated production of interferon-gamma. These immunostimulating actions of BV on NK activity and cytokine production can contribute to the understanding of the enhancement of the body's defense mechanisms against respiratory tract infections.
在体外对人外周血单个核细胞（PBMC）研究了泛福舒（BV）对不同免疫参数的影响。发现BV可增强PBMC的自然杀伤（NK）活性，并增加其自发和植物血凝素（PHA）诱导的肿瘤坏死因子-α和白细胞介素-2的产生，以及PHA刺激的干扰素-γ的产生。BV对NK活性和细胞因子产生的这些免疫刺激作用有助于理解机体针对呼吸道感染的防御机制增强。
