Gastrointestinal Unit, Medical Section, Herlev Hospital, University of Copenhagen, Herlev, Denmark.
J Crohns Colitis. 2009 Sep;3(3):207-11. doi: 10.1016/j.crohns.2009.03.007. Epub 2009 May 6.
Crohn's disease is a chronic inflammatory bowel disease often presenting with extra-intestinal manifestations. However, pulmonary involvement is quite rare. We report a case of Crohn's disease with pulmonary extra-intestinal manifestation (bronchiolitis obliterans organizing pneumonia-like changes) treated with infliximab. Furthermore, we present an overview of cases of inflammatory bowel disease with lung involvement, treated with tumor necrosis factor-α antagonists. In this case, when infliximab was given, a significant resolution of the pulmonary changes was achieved.
克罗恩病是一种慢性炎症性肠病，常伴有肠外表现。然而，肺部受累相当罕见。我们报告一例克罗恩病伴肺肠外表现（闭塞性细支气管炎机化性肺炎样改变），用英夫利昔单抗治疗。此外，我们还概述了用肿瘤坏死因子-α拮抗剂治疗的伴有肺部受累的炎症性肠病病例。在本例中，给予英夫利昔单抗后，肺部病变明显缓解。
