INSERM-Université Paris Sud U1014, Hôpital Paul Brousse, 14 rue Paul Vaillant Couturier, Villejuif Cedex, France.
Cancer Lett. 2011 Jun 28;305(2):144-9. doi: 10.1016/j.canlet.2010.11.007. Epub 2010 Dec 18.
Epstein-Barr virus (EBV) a ubiquitous gamma herpesvirus persists for life, generally without health consequences. However, it is associated with several well-recognized malignancies, such as Burkitt's lymphoma and nasopharyngeal carcinoma. A growing list of malignancies has been proposed to be EBV-associated: most of which are consistently EBV-positive whereas others show inconsistent results. The possible contribution of EBV to the development and/or progression of different "non-classical" tumors is discussed in terms of putative "non-traditional'' infection in EBV-related tumors.
爱泼斯坦-巴尔病毒（EBV）是一种普遍存在的γ疱疹病毒，可终身存在，通常不会对健康造成影响。然而，它与几种公认的恶性肿瘤有关，如伯基特淋巴瘤和鼻咽癌。越来越多的恶性肿瘤被认为与 EBV 有关：其中大多数是持续 EBV 阳性，而其他则显示不一致的结果。本文讨论了 EBV 在不同“非典型”肿瘤的发生和/或进展中的可能作用，认为 EBV 相关肿瘤存在“非传统”感染。
