• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Familial lung adenocarcinoma caused by the EGFR V843I germ-line mutation.

作者信息

Ohtsuka Kouki, Ohnishi Hiroaki, Kurai Daisuke, Matsushima Satsuki, Morishita Yukio, Shinonaga Mayumi, Goto Hajime, Watanabe Takashi

机构信息

Kyorin University School of Medicine, Tokyo, Japan.

出版信息

J Clin Oncol. 2011 Mar 10;29(8):e191-2. doi: 10.1200/JCO.2010.31.4492. Epub 2010 Dec 20.

DOI:10.1200/JCO.2010.31.4492
PMID:21172876
Abstract
摘要

相似文献

1
Familial lung adenocarcinoma caused by the EGFR V843I germ-line mutation.由EGFR V843I种系突变引起的家族性肺腺癌。
J Clin Oncol. 2011 Mar 10;29(8):e191-2. doi: 10.1200/JCO.2010.31.4492. Epub 2010 Dec 20.
2
Novel germline mutation: EGFR V843I in patient with multiple lung adenocarcinomas and family members with lung cancer.新型胚系突变：多发肺腺癌患者及肺癌家族成员中的EGFR V843I突变
Ann Thorac Surg. 2008 Apr;85(4):1430-2. doi: 10.1016/j.athoracsur.2007.10.012.
3
Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.肺癌的遗传易感性可能与表皮生长因子受体（EGFR）中的T790M耐药突变有关。
Nat Genet. 2005 Dec;37(12):1315-6. doi: 10.1038/ng1671. Epub 2005 Oct 30.
4
A dramatic lung cancer course in a patient with a rare EGFR germline mutation exon 21 V843I: Is EGFR TKI resistance predictable?罕见 EGFR 胚系突变exon21 V843I 患者的戏剧性肺癌病程：EGFR TKI 耐药是否可预测？
Lung Cancer. 2013 Apr;80(1):81-4. doi: 10.1016/j.lungcan.2012.11.013. Epub 2013 Feb 4.
5
Activating germline R776H mutation in the epidermal growth factor receptor associated with lung cancer with squamous differentiation.表皮生长因子受体中的种系R776H激活突变与肺鳞状分化癌相关。
J Clin Oncol. 2013 Apr 1;31(10):e161-4. doi: 10.1200/JCO.2012.42.1586. Epub 2013 Jan 28.
6
Modern treatment of lung cancer: case 1. Amplification and mutation of the epidermal growth factor receptor in metastatic lung cancer with remission from gefitinib.肺癌的现代治疗：病例1。转移性肺癌中表皮生长因子受体的扩增与突变及吉非替尼治疗后缓解
J Clin Oncol. 2005 Oct 20;23(30):7736-8. doi: 10.1200/JCO.2005.02.4760.
7
EGFR and K-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to EGFR inhibitors.肺上皮肿瘤谱系中的表皮生长因子受体（EGFR）和K-ras突变以及一种联合临床病理和分子评分系统的制定，以预测对EGFR抑制剂的临床反应性。
Am J Clin Pathol. 2009 Apr;131(4):478-89. doi: 10.1309/AJCPH0TRMPXVZW2F.
8
Cytomorphological correlates of epidermal growth factor receptor mutations in lung carcinoma.肺癌中表皮生长因子受体突变的细胞形态学相关性
Diagn Cytopathol. 2007 May;35(5):257-62. doi: 10.1002/dc.20617.
9
EGFR mutations and the terminal respiratory unit.表皮生长因子受体突变与终末呼吸单位。
Cancer Metastasis Rev. 2010 Mar;29(1):23-36. doi: 10.1007/s10555-010-9205-8.
10
[Should we always use EGFR mutation analysis prior to palliative firstline therapy of metastatic adenocarcinoma of the lung? Pro].在转移性肺腺癌的姑息一线治疗之前，我们是否应始终进行表皮生长因子受体（EGFR）突变分析？正方观点
Dtsch Med Wochenschr. 2012 Mar;137(12):592. doi: 10.1055/s-0031-1298873. Epub 2012 Mar 13.

引用本文的文献

1
The pathogenic germline ETV4 P433L mutation identified in multiple primary lung cancer affect tumor stem-like property by Wnt/β-catenin pathway.在多个原发性肺癌中鉴定出的致病变异体 ETV4 P433L 突变通过 Wnt/β-连环蛋白途径影响肿瘤干细胞样特性。
Cell Death Dis. 2024 Oct 10;15(10):738. doi: 10.1038/s41419-024-07129-z.
2
Benefits of osimertinib treat a lung adenocarcinoma patient with germline EGFR T790M, somatic EGFR 19-Del, TP53 and PIK3CA mutations.奥希替尼治疗一名具有胚系EGFR T790M、体细胞EGFR 19-缺失、TP53和PIK3CA突变的肺腺癌患者的益处。
Hered Cancer Clin Pract. 2024 Aug 19;22(1):13. doi: 10.1186/s13053-024-00286-4.
3
Lung cancer in patients who have never smoked - an emerging disease.
从不吸烟患者的肺癌——一种新出现的疾病。
Nat Rev Clin Oncol. 2024 Feb;21(2):121-146. doi: 10.1038/s41571-023-00844-0. Epub 2024 Jan 9.
4
Germline EGFR mutations in lung cancer (Review).肺癌中的种系表皮生长因子受体突变（综述）
Oncol Lett. 2023 May 16;26(1):282. doi: 10.3892/ol.2023.13868. eCollection 2023 Jul.
5
Two germline mutations can serve as genetic susceptibility screening makers for a lung adenocarcinoma family.两种种系突变可作为肺腺癌家族的遗传易感性筛查标志物。
J Cancer Res Clin Oncol. 2023 Aug;149(9):6541-6548. doi: 10.1007/s00432-023-04616-2. Epub 2023 Feb 13.
6
Cancer Predisposition Genes in Adolescents and Young Adults (AYAs): a Review Paper from the Italian AYA Working Group.青少年和青年癌症易感基因：意大利 AYA 工作组的综述论文。
Curr Oncol Rep. 2022 Jul;24(7):843-860. doi: 10.1007/s11912-022-01213-3. Epub 2022 Mar 23.
7
Pedigree analysis of the p.V1010M germline mutation in a family with a family history of non-small-cell lung cancer.对一个有非小细胞肺癌家族史的家庭中p.V1010M种系突变的系谱分析。
Ann Transl Med. 2022 Feb;10(3):154. doi: 10.21037/atm-21-6925.
8
Genomic Profiling of Lung Adenocarcinoma in Never-Smokers.非吸烟肺腺癌的基因组分析。
J Clin Oncol. 2021 Nov 20;39(33):3747-3758. doi: 10.1200/JCO.21.01691. Epub 2021 Sep 30.
9
Lung cancer screening: who pays? who receives?-the Chinese perspective.肺癌筛查：谁来买单？谁能受益？——中国视角
Transl Lung Cancer Res. 2021 May;10(5):2389-2394. doi: 10.21037/tlcr.2020.03.16.
10
Epidermal Growth Factor Receptor Expression and Resistance Patterns to Targeted Therapy in Non-Small Cell Lung Cancer: A Review.表皮生长因子受体表达与非小细胞肺癌靶向治疗耐药模式：综述。
Cells. 2021 May 14;10(5):1206. doi: 10.3390/cells10051206.