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在一个小容量中心,体外膜肺氧合用于支持急性心肌梗死导致心脏骤停的成年患者延长传统心肺复苏时间。

Extracorporeal membrane oxygenation to support prolonged conventional cardiopulmonary resuscitation in adults with cardiac arrest from acute myocardial infarction at a very low-volume centre.

作者信息

Liu Ying, Cheng Yi Tso, Chang Jui Chi, Chao Sheng Feng, Chang Bee Song

机构信息

Department of Thoracic and Cardiovascular Surgery, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, Province of China.

出版信息

Interact Cardiovasc Thorac Surg. 2011 Mar;12(3):389-93. doi: 10.1510/icvts.2010.256388. Epub 2010 Dec 20.

Abstract

We aimed to analyse the outcomes of the deployment of extracorporeal membrane oxygenation assisted cardiopulmonary resuscitation (E-CPR) 11 times for acute myocardial infarction (AMI) in 10 adult patients at a very low-volume (VLV) centre, where perfusionists or surgeons are not always available. We conducted a three-year retrospective chart review. E-CPR was performed 13 times in 12 adult patients who had cardiac arrest events and who underwent conventional CPR for longer than 10 min. We excluded other aetiologies that led to E-CPR. All 11 selected episodes of E-CPR were diagnosed as AMI. Seven patients (63.6%) were successfully weaned off extracorporeal membrane oxygenation (ECMO). Four patients survived to discharge without neurological deficits or other postE-CPR complications (36.3%). Seven patients died after E-CPR, and with one patient, there was no return of spontaneous beating during E-CPR (0.9%). Three patients died of unstable haemodynamics despite revascularisation of the coronary circulation. Three patients were successfully weaned off ECMO; however, they died subsequently of multiple organ dysfunction, unstable haemodynamic changes and septic shock from nosocomial infections, respectively. The outcome of E-CPR in adults with AMI was compared with previous studies at high-volume centres. Mortality or morbidity rates are not higher at a VLV centre.

摘要

我们旨在分析在一个极低容量(VLV)中心,10名成年患者因急性心肌梗死(AMI)接受11次体外膜肺氧合辅助心肺复苏(E-CPR)的结果,该中心灌注师或外科医生并非随时可用。我们进行了为期三年的回顾性病历审查。12名发生心脏骤停事件且接受传统心肺复苏超过10分钟的成年患者接受了13次E-CPR。我们排除了导致E-CPR的其他病因。所有11例选定的E-CPR病例均被诊断为AMI。7名患者(63.6%)成功脱离体外膜肺氧合(ECMO)。4名患者存活出院,无神经功能缺损或其他心肺复苏后并发症(36.3%)。7名患者在E-CPR后死亡,1名患者在E-CPR期间未恢复自主心跳(0.9%)。3名患者尽管冠状动脉循环血运重建,但死于血流动力学不稳定。3名患者成功脱离ECMO;然而,他们随后分别死于多器官功能障碍、血流动力学不稳定变化和医院感染引起的感染性休克。将AMI成年患者的E-CPR结果与高容量中心的既往研究进行了比较。在VLV中心,死亡率或发病率并不更高。

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