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成人及儿童体外心肺复苏:文献综述、已发布指南及儿科单中心项目建设经验

Extracorporeal cardiopulmonary resuscitation in adults and children: A review of literature, published guidelines and pediatric single-center program building experience.

作者信息

Olson Taylor, Anders Marc, Burgman Cole, Stephens Adam, Bastero Patricia

机构信息

Pediatric Critical Care Medicine, Children's National Hospital, Washington, DC, United States.

Department of Pediatrics, Baylor College of Medicine, Houston, TX, United States.

出版信息

Front Med (Lausanne). 2022 Nov 21;9:935424. doi: 10.3389/fmed.2022.935424. eCollection 2022.

DOI:10.3389/fmed.2022.935424
PMID:36479094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9720280/
Abstract

Extracorporeal cardiopulmonary resuscitation (ECPR) is an adjunct supportive therapy to conventional cardiopulmonary resuscitation (CCPR) employing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in the setting of refractory cardiac arrest. Its use has seen a significant increase in the past decade, providing hope for good functional recovery to patients with cardiac arrest refractory to conventional resuscitation maneuvers. This review paper aims to summarize key findings from the ECPR literature available to date as well as the recommendations for ECPR set forth by leading national and international resuscitation societies. Additionally, we describe the successful pediatric ECPR program at Texas Children's Hospital, highlighting the logistical, technical and educational features of the program.

摘要

体外心肺复苏(ECPR)是在难治性心脏骤停情况下,采用静脉 - 动脉体外膜肺氧合(VA - ECMO)辅助传统心肺复苏(CCPR)的一种支持性治疗方法。在过去十年中,其使用量显著增加,为难治性心脏骤停患者带来了良好功能恢复的希望。这篇综述文章旨在总结迄今为止ECPR文献中的关键发现以及国内外主要复苏协会提出的ECPR建议。此外,我们还描述了德克萨斯儿童医院成功的儿科ECPR项目,突出了该项目的后勤、技术和教育特点。

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本文引用的文献

1
Association between short-term neurological outcomes and extreme hyperoxia in patients with out-of-hospital cardiac arrest who underwent extracorporeal cardiopulmonary resuscitation: a retrospective observational study from a multicenter registry.体外心肺复苏后院外心脏骤停患者短期神经结局与极度高氧血症的关系:一项多中心登记的回顾性观察研究。
BMC Cardiovasc Disord. 2022 Apr 11;22(1):163. doi: 10.1186/s12872-022-02598-6.
2
The association of modifiable mechanical ventilation settings, blood gas changes and survival on extracorporeal membrane oxygenation for cardiac arrest.体外膜肺氧合治疗心脏骤停时可调节机械通气设置、血气变化与存活率的关系。
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Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.停搏期转运、体外心肺复苏术和即刻有创评估与治疗对难治性院外心脏骤停患者神经功能结局的影响:一项随机临床试验。
JAMA. 2022 Feb 22;327(8):737-747. doi: 10.1001/jama.2022.1025.
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In-Hospital Cardiac Arrest Survival in the United States During and After the Initial Novel Coronavirus Disease 2019 Pandemic Surge.美国在经历和度过 2019 年新型冠状病毒病疫情初期高峰期期间和之后院内心搏骤停存活率。
Circ Cardiovasc Qual Outcomes. 2022 Feb;15(2):e008420. doi: 10.1161/CIRCOUTCOMES.121.008420. Epub 2022 Jan 31.
5
ERC-ESICM guidelines on temperature control after cardiac arrest in adults.《成人心脏骤停后体温控制的 ERC-ESICM 指南》。
Intensive Care Med. 2022 Mar;48(3):261-269. doi: 10.1007/s00134-022-06620-5. Epub 2022 Jan 28.
6
Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association.《心脏病与卒中统计-2022 更新:美国心脏协会报告》。
Circulation. 2022 Feb 22;145(8):e153-e639. doi: 10.1161/CIR.0000000000001052. Epub 2022 Jan 26.
7
The epidemiology of out-of-hospital cardiac arrest in Australia and New Zealand: A binational report from the Australasian Resuscitation Outcomes Consortium (Aus-ROC).澳大利亚和新西兰院外心脏骤停的流行病学:来自澳大拉西亚复苏结果联盟(Aus-ROC)的一项双边报告。
Resuscitation. 2022 Mar;172:74-83. doi: 10.1016/j.resuscitation.2022.01.011. Epub 2022 Jan 22.
8
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Pediatr Qual Saf. 2022 Jan 21;7(1):e510. doi: 10.1097/pq9.0000000000000510. eCollection 2022 Jan-Feb.
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Resuscitation Using ECPR During In-Hospital Cardiac Arrest (RESCUE-IHCA) Mortality Prediction Score and External Validation.应用体外心肺复苏(ECPR)于院内心脏骤停患者的复苏(RESCUE-IHCA)死亡率预测评分及其外部验证。
JACC Cardiovasc Interv. 2022 Feb 14;15(3):237-247. doi: 10.1016/j.jcin.2021.09.032. Epub 2022 Jan 12.
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How effective is extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest? A systematic review and meta-analysis.体外心肺复苏(ECPR)对院外心脏骤停的效果如何?系统评价和荟萃分析。
Am J Emerg Med. 2022 Jan;51:127-138. doi: 10.1016/j.ajem.2021.08.072. Epub 2021 Sep 2.