University of Southern Denmark, Institute of Public Health, Odense, Denmark (DG-H, J. Nielsen, HS)
Health Economics Unit, Danish Institute for Health Services Research, Dampfaergvej, Denmark (DG-H)
Med Decis Making. 2011 Jan-Feb;31(1):E1-10. doi: 10.1177/0272989X10391268. Epub 2010 Dec 20.
When people make choices, they may have multiple options presented simultaneously or, alternatively, have options presented 1 at a time. It has been shown that if decision makers have little experience with or difficulties in understanding certain attributes, these attributes will have greater impact in joint evaluations than in separate evaluations. The authors investigated the impact of separate versus joint evaluations in a health care context in which laypeople were presented with the possibility of participating in risk-reducing drug therapies.
In a randomized study comprising 895 subjects aged 40 to 59 y in Odense, Denmark, subjects were randomized to receive information in terms of absolute risk reduction (ARR), relative risk reduction (RRR), number needed to treat (NNT), or prolongation of life (POL), all with respect to heart attack, and they were asked whether they would be willing to receive a specified treatment. Respondents were randomly allocated to valuing the interventions separately (either great effect or small effect) or jointly (small effect and large effect).
Joint evaluation reduced the propensity to accept the intervention that offered the smallest effect. Respondents were more sensitive to scale when faced with a joint evaluation for information formats ARR, RRR, and POL but not for NNT. Evaluability bias appeared to be most pronounced for POL and ARR.
Risk information appears to be prone to evaluability bias. This suggests that numeric information on health gains is difficult to evaluate in isolation. Consequently, such information may bear too little weight in separate evaluations of risk-reducing interventions.
当人们做出选择时,他们可能会同时面临多种选择,或者一次只呈现一种选择。已经表明,如果决策者对某些属性的经验很少或理解困难,这些属性在联合评估中比单独评估中具有更大的影响。作者在一个医疗保健背景下研究了单独评估和联合评估的影响,其中非专业人士有参与降低风险药物治疗的可能性。
在丹麦奥登塞的一项随机研究中,有 895 名年龄在 40 至 59 岁的受试者参与,他们被随机分配接受关于绝对风险降低(ARR)、相对风险降低(RRR)、需要治疗的人数(NNT)或延长生命(POL)的信息,所有这些都与心脏病发作有关,并被问及他们是否愿意接受特定的治疗。受访者被随机分配分别(大效果或小效果)或联合(小效果和大效果)评估干预措施。
联合评估降低了接受提供最小效果的干预措施的倾向。受访者在面对 ARR、RRR 和 POL 信息格式的联合评估时对量表更敏感,但对 NNT 不敏感。评估能力偏差似乎对 POL 和 ARR 最为明显。
风险信息似乎容易受到评估能力偏差的影响。这表明,关于健康收益的数字信息难以单独评估。因此,在单独评估降低风险的干预措施时,这种信息可能没有太大的权重。