Barry University School of Podiatric Medicine and Surgery, Miami Shores, Florida, USA.
Adv Skin Wound Care. 2011 Jan;24(1):15-7. doi: 10.1097/01.ASW.0000392923.37852.43.
Thromboangiitis obliterans, or Buerger disease, is a debilitating vascular disease with a well-known pronounced link to cigarette smoking and, more specifically, to the nicotine component of tobacco inhalation. Buerger disease is an inflammatory occlusive disorder that primarily affects the medium and small vessels of the extremities. In the present case report, a 46-year-old man, nonforthcoming smoker, presented to the authors' clinic with a deep ulcer at the head of the second metatarsal. Evidently, although the patient continued to smoke, the ulcer responded to therapy but regressed. Once the history was elaborated, the patient stopped smoking, and the ulcer healed completely within 2 months. Follow-up appointments proved to be unremarkable and to the authors' knowledge, there has not been a reoccurrence, and the patient remains tobacco-free.
血栓闭塞性脉管炎,或伯格氏病,是一种使人虚弱的血管疾病,与吸烟有明显的关联,尤其是与吸烟吸入的尼古丁成分有关。伯格氏病是一种炎症闭塞性疾病,主要影响四肢的中、小血管。在本病例报告中,一名 46 岁的男性,非吸烟者,因第二跖骨头的深部溃疡到作者的诊所就诊。显然,尽管患者继续吸烟,但溃疡对治疗有反应并有所缓解。一旦详细了解了病史,患者就戒烟了,溃疡在 2 个月内完全愈合。随访没有发现异常,据作者所知,溃疡没有再发,患者也没有再吸烟。