Ambrosi C N, Rapini R P
Department of Pathology, University of Texas Medical School, Houston.
Cutis. 1993 Mar;51(3):180-2.
Buerger's disease (thromboangiitis obliterans) is an uncommon vascular occlusive disease most commonly affecting the lower extremities of young male tobacco smokers. We report the case of a thirty-five-year-old man who presented with nonhealing ulcerations of several toes. Arteriography revealed severe bilateral vascular occlusion. The patient failed to respond to intensive topical care, nifedipine, pentoxifylline, hyperbaric oxygen, intravenous antibiotics, and whirlpool. He continued to smoke, and eventually became septic, requiring amputations of his gangrenous left second toe and right leg below the knee.
血栓闭塞性脉管炎是一种罕见的血管闭塞性疾病，最常影响年轻男性烟民的下肢。我们报告了一例35岁男性患者，其数个脚趾出现不愈合溃疡。血管造影显示双侧严重血管闭塞。该患者对强化局部护理、硝苯地平、己酮可可碱、高压氧、静脉抗生素及漩涡浴治疗均无反应。他继续吸烟，最终发生败血症，需要截去坏疽的左第二趾及右膝以下小腿。
