Writer Brian W, Schillerstrom Jason E, Regwan Heather K, Harlan Brent S
Department of Psychiatry, San Antonio Military Medical Center, Lackland Air Force Base, TX, USA.
J Rehabil Res Dev. 2010;47(9):841-50. doi: 10.1682/jrrd.2009.10.0162.
Executive Clock Drawing Tasks (CLOX parts 1 and 2) can predict functional impairment. This study determined the correlation between CLOX and other psychometric screening instruments with the Structured Assessment of Independent Living Skills (SAILS)-defined performance-based functional status in people with combat-related mild traumatic brain injury (TBI) and comorbid posttraumatic stress disorder (PTSD). We hypothesized that CLOX would correlate significantly with functional performance. This prospective, cross-sectional study design determined the correlation between a structured neuropsychological battery and functional status assessment. We calculated Pearson correlation coefficients between neuropsychological instruments and functional status scores. We entered neuropsychological measures correlating p < 0.1 with functional status into a linear regression model to determine independent contributions. Fifteen Operation Iraqi Freedom veterans participated. Only CLOX1 correlated significantly with functional competency and efficiency. Only mean CLOX1 scores were significantly lower in those scoring below the median for SAILS competency and in those scoring above the median for SAILS efficiency. CLOX1 contributed significant variance to functional status independent of mood or anxiety symptoms and was not affected by age or time since injury. Executive dysfunction per the brief, easily administered CLOX1 is sensitive to functional status following combat-related mild TBI, independent of PTSD anxiety with or without depression.
执行时钟绘图任务(CLOX第1部分和第2部分)可以预测功能障碍。本研究确定了在患有与战斗相关的轻度创伤性脑损伤(TBI)和共病创伤后应激障碍(PTSD)的人群中,CLOX与其他心理测量筛查工具与基于结构化独立生活技能评估(SAILS)定义的基于表现的功能状态之间的相关性。我们假设CLOX与功能表现将显著相关。这项前瞻性横断面研究设计确定了一套结构化神经心理学测试组合与功能状态评估之间的相关性。我们计算了神经心理学工具与功能状态评分之间的Pearson相关系数。我们将与功能状态相关性p<0.1的神经心理学测量指标纳入线性回归模型,以确定独立贡献。15名伊拉克自由行动退伍军人参与了研究。只有CLOX1与功能能力和效率显著相关。在SAILS能力得分低于中位数的人群以及SAILS效率得分高于中位数的人群中,只有CLOX1的平均得分显著较低。CLOX1对功能状态的显著变异有贡献,独立于情绪或焦虑症状,且不受年龄或受伤时间的影响。根据简短、易于实施的CLOX1评估的执行功能障碍对与战斗相关的轻度TBI后的功能状态敏感,独立于伴有或不伴有抑郁的PTSD焦虑。