Brenner Lisa A, Ladley-O'Brien Susan E, Harwood Jeri E F, Filley Christopher M, Kelly James P, Homaifar Beeta Y, Adler Lawrence E
VA VISN 19 Mental Illness Research, Education and Clinical Center (MIRECC), 1055 Clermont Street, Denver, CO 80220, USA.
Mil Med. 2009 Apr;174(4):347-52. doi: 10.7205/milmed-d-01-5808.
Seventy-two veterans with traumatic brain injury (TBI), posttraumatic stress disorder (PTSD), or both participated in assessment procedures to evaluate between group differences. Half the sample was randomly selected for magnetic resonance imaging (MRI). Neurologic examinations were conducted using the Neurologic Rating Scale (NRS). Neuropsychological measures included the Paced Auditory Serial Addition Test (PASAT), Rey Auditory Verbal Learning Test (RAVLT), Conners' Continuous Performance Test II (CPT II), and Halstead Impairment Index (HII) including the Booklet Category Test (BCT). Data were analyzed using linear regression. Participants with moderate/ severe TBI were significantly more likely to have trauma-related imaging findings, and more severe TBI predicted lower scores on the NRS. No significant between-group differences were identified on the HII, PASAT, RAVLT, or CPT II. TBI group performance was significantly better on the BCT. More severe TBI predicted abnormal imaging findings and lower NRS scores. Hypothesized between-group differences on neuropsychological measures were not supported.
72名患有创伤性脑损伤（TBI）、创伤后应激障碍（PTSD）或两者皆有的退伍军人参与了评估程序，以评估组间差异。样本的一半被随机选取进行磁共振成像（MRI）检查。使用神经学评定量表（NRS）进行神经学检查。神经心理学测量包括听觉连续加法测验（PASAT）、雷伊听觉词语学习测验（RAVLT）、康纳斯连续操作测验第二版（CPT II）以及包括分类测验手册（BCT）在内的霍尔斯特德损伤指数（HII）。采用线性回归分析数据。中度/重度TBI患者出现创伤相关影像学表现的可能性显著更高，且更严重的TBI预示着NRS得分更低。在HII、PASAT、RAVLT或CPT II上未发现显著的组间差异。TBI组在BCT上的表现显著更好。更严重的TBI预示着异常的影像学表现和更低的NRS得分。神经心理学测量中假设的组间差异未得到支持。
