Sugiura Mayumi, Ozaki Yasuhiko, Katano Kinue
Department of Obstetrics and Gynecology, Nagoya City University, Graduate School of Medical Sciences.
Nihon Rinsho. 2010 Dec;68(12):2351-6.
Recurrent miscarriage is classically defined as three or more consecutive pregnancy losses. Established causes of recurrent miscarriage are antiphospholipid antibodies, uterine anomalies and abnormal chromosomes in either partner, particularly translocations. Embryonic aneuploidy is the most important cause of miscarriage before ten weeks' gestation. It can be speculated that about 51% of patients with a history of three miscarriages experienced these because of abnormal embryonic karyotypes. It is not necessary to give any medication for such cases caused by an abnormal embryonic karyotype. Psychological support might be the most important requirement to continue conceiving till live birth results.
复发性流产的经典定义是连续发生三次或三次以上的妊娠丢失。复发性流产的确立病因包括抗磷脂抗体、子宫异常以及夫妻双方任何一方的染色体异常，尤其是染色体易位。胚胎非整倍体是妊娠10周前流产的最重要原因。据推测，有三次流产史的患者中，约51%是由于胚胎核型异常导致流产。对于由胚胎核型异常引起的此类情况，无需给予任何药物治疗。心理支持可能是继续受孕直至分娩成功的最重要需求。
