Cole Tim J, Williams Anthony F, Wright Charlotte M
Medical Statistics, UCL Institute of Child Health, University College London, London, UK.
Ann Hum Biol. 2011 Jan;38(1):7-11. doi: 10.3109/03014460.2011.544139.
The adoption in May 2009 by the UK of the WHO 2006 standard necessitated the provision of UK-based birth centiles for pre-term infants. The pre-existing British 1990 reference birth centiles, used in the UK since 1995, had been biased by the inclusion of post-natal data.
To describe the construction of new UK birth centiles for weight, length and head circumference, based on British 1990 reference data, but excluding post-natal data.
Birth data from the five original studies, collected between 1983-1993, were pooled and analysed by the LMS method, for the sexes separately. In addition, sex-specific composite centiles were constructed for infants born at term (37-42 completed weeks).
The birth data included 9443 weights, 985 lengths and 1841 head circumferences, covering 23-44 weeks gestation. The analysis provided LMS tables defining reference centiles for weight and head circumference from 23-42 weeks and for length from 26-42 weeks. The term centiles are for use at age 0 on the post-natal 0-1 year chart.
These new centiles, replacing those of the British 1990 reference, are more accurate than their predecessors which were biased due to the inclusion of post-natal data.
2009年5月英国采用了世界卫生组织2006年的标准,因此有必要提供英国早产儿的出生百分位数。自1995年起在英国使用的1990年英国参考出生百分位数,因纳入了产后数据而存在偏差。
基于1990年英国参考数据,但不包括产后数据,描述英国新的体重、身长和头围出生百分位数的构建。
对1983年至1993年期间收集的五项原始研究中的出生数据进行汇总,并采用LMS方法分别对性别进行分析。此外,还为足月儿(37 - 42足周)构建了特定性别的综合百分位数。
出生数据包括9443例体重、985例身长和1841例头围,涵盖23 - 44周的孕周。分析提供了LMS表格,定义了23 - 42周体重和头围以及26 - 42周身长的参考百分位数。足月儿百分位数用于产后0 - 1岁图表上的0岁。
这些新的百分位数取代了1990年英国参考百分位数,比其前身更准确,后者因纳入产后数据而存在偏差。