Chinese Evidence-Based Medicine Centre, West China Hospital, Sichuan University, Chengdu, China.
BJOG. 2011 Mar;118(4):400-9. doi: 10.1111/j.1471-0528.2010.02802.x. Epub 2010 Dec 23.
Urinary catheterisation, which is associated with 80% of urinary tract infections (UTIs), is routinely performed prior to caesarean section without justification from the best available research evidence.
To assess whether it is necessary to place indwelling urinary catheters routinely in caesarean section, and to determine the effects of this procedure on UTIs, urinary retention, intra-operative difficulties, operative complications, as well as other outcomes.
MEDLINE, EMBASE, the Cochrane Controlled Trials Register, POPLINE, SCI, Chinese Biomedical Literature Database, China Academic Journals Full-Text Database and Chinese Scientific Journals Database were searched in all languages, together with reference lists of the retrieved papers.
Randomised controlled trials (RCTs) and nonrandomised controlled trials (NRCTs) comparing the use versus nonuse of indwelling urinary catheters in caesarean section were included.
Two reviewers independently selected the studies and extracted the data. Results from the trials were combined to calculate relative risks (RRs) for dichotomous outcomes and mean differences (MDs) for continuous outcomes, with 95% confidence intervals (CIs).
Three trials (two RCTs and one NRCT) were included, involving a total of 1084 participants. Compared with the use of indwelling urinary catheters, nonuse had a significantly lower incidence of UTIs [RR 0.08; 95% CI 0.01, 0.64 (study design: RCT); RR 0.10; 95% CI 0.02, 0.57 (study design: NRCT)], a lower rate of discomfort at first voiding (RR 0.06; 95% CI 0.03, 0.12), less time until first voiding (MD -16.81; 95% CI -17.31, -16.31) and less time until ambulation (MD -6.01; 95% CI -6.68, -5.35); there were no statistically significant differences in the rate of urinary retention [RR 5.00; 95% CI 0.24, 103.18 (study design: RCT); RR 0.74; 95% CI 0.04, 15.18 (study design: NRCT)], operating time (MD -1.10; 95% CI -3.32, 1.12) and rate of intra-operative difficulties (RR 1.00; 95% CI -3.32, 1.12).
The nonuse of indwelling urinary catheters in caesarean section is associated with less UTIs and no increase in either urinary retention or intra-operative difficulties. Our results suggest that the routine use of indwelling urinary catheters for caesarean delivery in haemodynamically stable patients is not necessary, and can be harmful. However, better and larger randomised trials are needed to confirm these findings.
导尿术与 80%的尿路感染(UTI)相关,在剖宫产手术前常规进行导尿术,但没有最好的现有研究证据来证明其合理性。
评估在剖宫产手术中是否有必要常规留置导尿管,并确定该操作对 UTI、尿潴留、术中困难、手术并发症以及其他结果的影响。
使用所有语言在 MEDLINE、EMBASE、Cochrane 对照试验登记处、POPLINE、SCI、中国生物医学文献数据库、中国学术期刊全文数据库和中国科学期刊数据库中进行检索,并检索了检索文献的参考文献列表。
纳入了比较剖宫产术使用与不使用留置导尿管的随机对照试验(RCT)和非随机对照试验(NRCT)。
两名评审员独立选择研究并提取数据。对试验结果进行合并,计算二分类结局的相对风险(RR)和连续结局的均数差(MD),置信区间(CI)为 95%。
纳入了三项试验(两项 RCT 和一项 NRCT),共涉及 1084 名参与者。与使用留置导尿管相比,不使用留置导尿管可显著降低 UTI 的发生率[RR 0.08;95%CI 0.01,0.64(研究设计:RCT);RR 0.10;95%CI 0.02,0.57(研究设计:NRCT)],首次排尿时不适感的发生率更低[RR 0.06;95%CI 0.03,0.12],首次排尿时间更短[MD-16.81;95%CI-17.31,-16.31],下床活动时间更短[MD-6.01;95%CI-6.68,-5.35];尿潴留发生率无统计学差异[RR 5.00;95%CI 0.24,103.18(研究设计:RCT);RR 0.74;95%CI 0.04,15.18(研究设计:NRCT)],手术时间[MD-1.10;95%CI-3.32,1.12]和术中困难发生率[RR 1.00;95%CI-3.32,1.12]。
在剖宫产手术中不使用留置导尿管可降低 UTI 的发生率,且不会增加尿潴留或术中困难的发生率。我们的研究结果表明,在血流动力学稳定的患者中,常规使用留置导尿管进行剖宫产分娩是不必要的,而且可能有害。但是,需要进行更好和更大规模的随机试验来证实这些发现。