Regional Intensive Care Unit, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland.
Crit Care. 2010;14(6):1012. doi: 10.1186/cc9359. Epub 2010 Dec 20.
Post hoc analyses from the B-type natriuretic peptide for Acute Shortness of Breath Evaluation (BASEL)-II-ICU study suggest an association between beta-blocker usage at admission and improved mortality in patients treated in the intensive care unit for acute respiratory failure. Although this evidence is encouraging, there is a need for a phase 2 proof-of-concept randomized controlled trial of beta-blocker therapy in patients admitted with acute respiratory failure.
来自 B 型利钠肽用于急性呼吸困难评估（BASEL）-II-ICU 研究的事后分析表明，在因急性呼吸衰竭接受重症监护治疗的患者中，入院时使用β受体阻滞剂与死亡率降低有关。尽管这一证据令人鼓舞，但仍需要开展一项 2 期以急性呼吸衰竭入院患者为研究对象的β受体阻滞剂治疗的概念验证随机对照试验。
