大鼠腹侧前列腺中的溶酶体酶分泌。睾酮和二丁酰环磷酸腺苷的促分泌作用。
Lysosomal enzyme secretion in rat ventral prostate. Secretagogue action of testosterone and dibutyryl cyclic AMP.
作者信息
Koenig H, Lu C Y, Bakay R
出版信息
Acta Biol Med Ger. 1977;36(11-12):1653-9.
PMID:211766
Abstract
Rat ventral prostate slices, when incubated in vitro, secrete protein, lysosomal enzymes and newly phosphorylated components in a time- and temperature-dependent manner. Testosterone and dibutyryl cyclic AMP immediately stimulate secretion and 32Pi incorporation. Acid phosphatase and beta-N-acetylhexosaminidase are secreted as acidic isoenzymes presumably contained within primary lysosomes.
摘要
大鼠腹侧前列腺切片在体外培养时，会以时间和温度依赖的方式分泌蛋白质、溶酶体酶和新磷酸化的成分。睾酮和二丁酰环磷酸腺苷会立即刺激分泌和32Pi掺入。酸性磷酸酶和β-N-乙酰己糖胺酶以酸性同工酶的形式分泌，推测其存在于初级溶酶体内。
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