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一项关于心血管疾病患者口腔健康促进活动效果的系统评价。

A systematic review of the effectiveness of oral health promotion activities among patients with cardiovascular disease.

机构信息

Oral Rehabilitation 4/F, 34 Hospital Road, Prince Philip Dental Hospital, Sai Ying Pun, Hong Kong, China.

出版信息

Int J Cardiol. 2011 Sep 15;151(3):261-7. doi: 10.1016/j.ijcard.2010.11.014. Epub 2010 Dec 21.

DOI:10.1016/j.ijcard.2010.11.014
PMID:21176980
Abstract

AIMS

This study aimed to review the effectiveness of oral health promotion activities conducted among patients with cardiovascular disease.

METHODS AND RESULTS

Three electronic databases were searched for effective papers using standardized search methods, and key findings of effective studies were summarized. The initial search yielded 3101 papers but only 8 studies met the criteria for this review: 3 were randomized controlled studies, 3 were pre-/post group interventions, 1 was a randomized split-mouth study, and 1 was a quasi-experimental study. Studies retrieved concerned oral health promotion activities in patients with coronary heart disease, hypertension, heart transplantation, and stroke. Interventions comprised periodontal treatment performed by dental personnel, and oral hygiene interventions provided by nursing home care assistants. Outcomes included improvements in periodontal health, and modifications of systemic inflammatory markers. No studies, however, evaluated the effects of oral health promotion interventions on oral microflora.

CONCLUSION

There are limited studies on the efficacy of oral health promotion activities in patients with cardiovascular disease, particularly stroke patients. Oral health promotion activities appear to produce improvements in periodontal health, and also result in changes to systemic markers of inflammation and endothelial function (at least) in the short term. Whether these effects can ultimately lower the risk of secondary cardiovascular events has not yet been determined.

摘要

目的

本研究旨在回顾针对心血管疾病患者开展的口腔健康促进活动的效果。

方法和结果

采用标准化检索方法,对三个电子数据库中的有效文献进行检索,总结有效研究的主要发现。最初的检索得到 3101 篇论文,但只有 8 项研究符合本综述的标准:3 项为随机对照研究,3 项为预-/后组干预研究,1 项为随机分组对照研究,1 项为准实验研究。检索到的研究涉及冠心病、高血压、心脏移植和中风患者的口腔健康促进活动。干预措施包括由牙科医务人员进行的牙周治疗和由养老院护理助理提供的口腔卫生干预。结果包括牙周健康的改善和系统性炎症标志物的改变。然而,没有研究评估口腔健康促进干预对口腔微生物群的影响。

结论

针对心血管疾病患者(尤其是中风患者)的口腔健康促进活动的疗效研究有限。口腔健康促进活动似乎在短期内可改善牙周健康,并可改变系统性炎症标志物和内皮功能(至少)。这些影响是否最终能降低二次心血管事件的风险仍未确定。

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