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[慢性角膜缘溃疡引发的结膜表皮样癌]

[Conjunctival epidermoid carcinoma revealed by a chronic limbic corneal ulceration].

作者信息

Janin-Manificat H, Gambrelle J, Mege-Lechevallier F, Aptel F, Beccat S, Denis P, Burillon C

机构信息

Service d'ophtalmologie, pavillon C, hôpital Édouard-Herriot, hospices civils de Lyon, 5, place d'Arsonval, 69003 Lyon, France.

出版信息

J Fr Ophtalmol. 2011 Feb;34(2):108-12. doi: 10.1016/j.jfo.2010.10.005. Epub 2010 Dec 21.

DOI:10.1016/j.jfo.2010.10.005
PMID:21176993
Abstract

PURPOSE

Conjunctival epidermoid carcinoma (CEC) is a rare tumor affecting mainly the perilimbal region of the bulbar conjunctiva. We report an atypical presentation of a CEC mimicking a Mooren pseudo-ulcer.

CASE REPORT

A 78-year-old man presented a limbic corneal ulcer of the left eye that had appeared a few months before. Ophthalmologic examination showed a thinning limbic corneal ulceration, associated with substantial conjunctival thickening. The diagnosis of Mooren pseudo-ulcer was first suspected. Etiological investigations were negative. The worsening of the corneal ulcer led us to perform surgical excision on the conjunctiva around the ulcer. Histologic examination concluded in an invasive conjunctival carcinoma. Adjuvant radiotherapy was required because of incomplete surgical excision and chorion tumoral invasion.

摘要

目的

结膜表皮样癌(CEC)是一种罕见肿瘤,主要累及球结膜的角膜缘区域。我们报告一例模仿蚕蚀性假溃疡的CEC非典型表现。

病例报告

一名78岁男性出现数月前出现的左眼角膜缘溃疡。眼科检查显示角膜缘变薄性溃疡,伴有结膜明显增厚。首先怀疑为蚕蚀性假溃疡诊断。病因学检查为阴性。角膜溃疡的恶化促使我们对溃疡周围的结膜进行手术切除。组织学检查确诊为浸润性结膜癌。由于手术切除不完全和肿瘤侵犯脉络膜,需要辅助放疗。

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