Hassani R Tahiri Joutei, Brasnu E, Amar N, Gheck L, Labbé A, Sterkers M, Baudouin C
Service d'Ophtalmologie III, Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris, France.
J Fr Ophtalmol. 2010 Mar;33(3):163-8. doi: 10.1016/j.jfo.2010.01.006. Epub 2010 Feb 13.
Ocular surface squamous neoplasia (OSSN) is the most common conjunctival and limbic malignant tumor that could resemble a pterygium in the early phase of the disease.
We report the case of a woman who presented with a limbic tumor of the left eye that was mistakenly diagnosed as a pterygium. An in vivo confocal microscopy examination using the HRTII Rostock Cornea Module and a surgical biopsy were performed. The in vivo confocal microscopy findings and the slit lamp examination showed characteristics that strongly supported the diagnosis of OSSN, and the histological examination of both biopsy and surgical exeresis (exenteration) confirmed the diagnosis of epidermoid carcinoma.
This case report underlines the value of in vivo confocal microscopy in the diagnosis of OSSN, particularly epidermoid carcinoma. This device could be helpful for the early differential diagnosis with pterygium.
眼表鳞状上皮肿瘤（OSSN）是最常见的结膜和角膜缘恶性肿瘤，在疾病早期可能类似翼状胬肉。
我们报告一例左眼角膜缘肿瘤被误诊为翼状胬肉的女性病例。使用HRTII罗斯托克角膜模块进行了共聚焦显微镜活体检查，并进行了手术活检。共聚焦显微镜活体检查结果和裂隙灯检查显示出强烈支持OSSN诊断的特征，活检和手术切除（眼球摘除）的组织学检查证实为表皮样癌。
本病例报告强调了共聚焦显微镜活体检查在OSSN诊断中的价值，尤其是在表皮样癌诊断方面。该设备有助于与翼状胬肉进行早期鉴别诊断。
