胃肠道间质瘤（GISTs）：病例报告及文献综述
Gastrointestinal stromal tumours (GISTs): case report and review of the literature.
作者信息
Al-Amri A M, Shawarbi M A, El-Hassan A Y, Al-Johi K S
机构信息
Department of Internal Medicine, King Fahd Hospital of the University, Al-Khobar, Saudi Arabia.
出版信息
Gulf J Oncolog. 2011 Jan(9):57-60.
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract, the majority of which is KIT (CD117) positive. In this case report, we describe a case of recurrent and metastatic GIST who presented with hepatic and brain metastases. Despite the patient's GISTs was negative for c-Kit (CD 117), he responded to imatinib mesylate (Glivec) treatment with complete resolution of his liver and brain lesions. The patient has been and still in complete remission for 18 months of follow-up.
胃肠道间质瘤（GIST）是胃肠道最常见的间叶组织肿瘤，其中大多数为KIT（CD117）阳性。在本病例报告中，我们描述了1例复发性和转移性GIST患者，其出现肝转移和脑转移。尽管该患者的GISTs c-Kit（CD 117）为阴性，但他对甲磺酸伊马替尼（格列卫）治疗有反应，肝脏和脑部病变完全消退。在18个月的随访中，该患者一直处于且仍然处于完全缓解状态。
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