Department of Hematology, Acute Leukemia and Stem Cell Transplantation Unit, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.
J Antimicrob Chemother. 2011 Jan;66 Suppl 1:i37-43. doi: 10.1093/jac/dkq440.
Invasive mould disease is a growing threat for immunocompromised patients. The optimum time to use mould-active antifungal agents is much debated. Current approaches to antifungal prophylaxis, early treatment (empirical and pre-emptive therapy) and treatment of documented mould infections in onco-haematology patients are discussed.
侵袭性霉菌病是免疫功能低下患者日益面临的威胁。目前,对于使用抗霉菌活性的抗真菌药物的最佳时机存在广泛争议。本文讨论了肿瘤血液病患者中抗真菌预防、早期治疗(经验性和抢先治疗)以及确诊霉菌感染的治疗方法。