Bergman B, Hedner T, Lundborg P
Acta Obstet Gynecol Scand. 1978;57(4):323-6. doi: 10.3109/00016347809154025.
The pressure-volume relationship in preterm rabbit lung was studied at 28 days of gestation. Injection of 0.1 mg terbutaline, a selective beta2-receptor stimulating drug, significantly increased the volume of air at equivalent low transpulmonary pressures, compared to a saline treated group and an untreated group. These findings indicate an increased pulmonary distensibility of the fetal rabbit lung after terbutaline administration. The mechanism of action is discussed and surfactant mediated effects are suggested to be the probable explanation.
在妊娠28天时研究了早产兔肺的压力-容积关系。与生理盐水处理组和未处理组相比，注射0.1毫克特布他林（一种选择性β2受体激动剂）后，在同等低跨肺压下，空气量显著增加。这些发现表明，给予特布他林后，胎兔肺的肺扩张性增加。文中讨论了其作用机制，并认为表面活性剂介导的效应可能是其原因。
