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本文引用的文献

1
Successful treatment of mediastinitis in a young child by omental translocation following extracardiac Fontan graft placement.
World J Pediatr Congenit Heart Surg. 2014 Oct;5(4):608-10. doi: 10.1177/2150135114539170.
2
In vitro efficacy of antibiotic beads in treating abdominal vascular graft infections.抗生素珠在治疗腹部血管移植感染中的体外疗效。
J Vasc Surg. 2015 Oct;62(4):1048-53. doi: 10.1016/j.jvs.2014.03.241. Epub 2014 Apr 16.
3
Mediastinitis following pediatric cardiac surgery.小儿心脏手术后纵隔炎
J Card Surg. 2014 Jan;29(1):74-82. doi: 10.1111/jocs.12243. Epub 2013 Nov 25.
4
Outcomes of infected abdominal aortic grafts managed with antimicrobial therapy and graft retention in an unselected cohort.未选择队列中使用抗菌治疗和保留移植物治疗感染性腹主动脉移植物的结果。
Eur J Vasc Endovasc Surg. 2013 Apr;45(4):373-80. doi: 10.1016/j.ejvs.2013.01.019.
5
Antibiotic-impregnated beads for the treatment of aortic graft infection.抗生素浸渍珠治疗主动脉移植物感染。
Ann Thorac Surg. 2012 Mar;93(3):984-5. doi: 10.1016/j.athoracsur.2011.07.066.
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Mediastinitis in pediatric cardiac surgery: Prevention, diagnosis and treatment.小儿心脏手术中的纵隔炎:预防、诊断与治疗
World J Cardiol. 2010 Nov 26;2(11):391-8. doi: 10.4330/wjc.v2.i11.391.
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A prospective, randomized clinical trial comparing an antibiotic-impregnated bioabsorbable bone substitute with standard antibiotic-impregnated cement beads in the treatment of chronic osteomyelitis and infected nonunion.一项前瞻性、随机临床试验比较了抗生素浸渍的可吸收骨替代物与标准抗生素浸渍的水泥珠在治疗慢性骨髓炎和感染性骨不连中的疗效。
J Orthop Trauma. 2010 Aug;24(8):483-90. doi: 10.1097/BOT.0b013e3181df91d9.
8
Options for managing infected ascending aortic grafts.
J Thorac Cardiovasc Surg. 2007 Oct;134(4):839-43. doi: 10.1016/j.jtcvs.2007.05.059.
9
Use of antibiotic-loaded polymethylmethacrylate beads for the treatment of extracavitary prosthetic vascular graft infections.使用载抗生素的聚甲基丙烯酸甲酯珠治疗腔外人工血管移植感染。
J Vasc Surg. 2006 Oct;44(4):757-61. doi: 10.1016/j.jvs.2006.05.056.
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Managing sternal osteomyelitis with antibiotic bead implantation.
Asian Cardiovasc Thorac Ann. 2006 Apr;14(2):e41-2. doi: 10.1177/021849230601400233.

使用抗生素浸润珠成功挽救化脓性纵隔炎背景下的心外膜Fontan手术

Successful Salvage of an Extracardiac Fontan in the Setting of Purulent Mediastinitis using Antibiotic-Impregnated Beads.

作者信息

Coghill Matthew T, Wallis Gonzalo A, Kirshbom Paul M, Maxey Thomas S

机构信息

Congenital Heart Center, Levine Children's Hospital, Charlotte, North Carolina.

出版信息

J Pediatr Intensive Care. 2018 Sep;7(3):163-165. doi: 10.1055/s-0038-1624562. Epub 2018 Feb 6.

DOI:10.1055/s-0038-1624562
PMID:31073489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6260353/
Abstract

Post-cardiotomy mediastinitis is an especially serious complication after the implantation of prosthetic vascular grafts. Standard of care is irrigation, debridement, and removal of all prosthetic material present in the surgical field. The use of antibiotic impregnated beads at the site of infection has been reported in the salvage of vascular grafts in the adult population. We present the case of a 3-year-old child with hypoplastic left heart syndrome who developed mediastinitis following the Fontan operation. In a nontraditional approach, the Fontan conduit, which was surrounded by gross purulence, was successfully salvaged with the adjunctive use of vancomycin-impregnated beads.

摘要

心脏手术后纵隔炎是人工血管移植术后一种特别严重的并发症。治疗标准是冲洗、清创以及清除手术区域内所有的人工材料。在成人血管移植挽救治疗中,已报道在感染部位使用抗生素浸渍珠。我们报告了一名3岁患有左心发育不全综合征的儿童,其在Fontan手术后发生纵隔炎。采用非传统方法,通过辅助使用万古霉素浸渍珠成功挽救了被大量脓液包围的Fontan导管。