Laboratory of Psychophysiology, Faculdade da Saúde, Universidade Metodista de São Paulo, São Paulo, Brazil.
PLoS One. 2010 Dec 17;5(12):e15022. doi: 10.1371/journal.pone.0015022.
In this study we analyzed the topography of induced cortical oscillations in 20 healthy individuals performing simple attention tasks. We were interested in qualitatively replicating our recent findings on the localization of attention-induced beta bands during a visual task [1], and verifying whether significant topographic changes would follow the change of attention to the auditory modality. We computed corrected latency averaging of each induced frequency bands, and modeled their generators by current density reconstruction with Lp-norm minimization. We quantified topographic similarity between conditions by an analysis of correlations, whereas the inter-modality significant differences in attention correlates were illustrated in each individual case. We replicated the qualitative result of highly idiosyncratic topography of attention-related activity to individuals, manifested both in the beta bands, and previously studied slow potential distributions [2]. Visual inspection of both scalp potentials and distribution of cortical currents showed minor changes in attention-related bands with respect to modality, as compared to the theta and delta bands, known to be major contributors to the sensory-related potentials. Quantitative results agreed with visual inspection, supporting to the conclusion that attention-related activity does not change much between modalities, and whatever individual changes do occur, they are not systematic in cortical localization across subjects. We discuss our results, combined with results from other studies that present individual data, with respect to the function of cortical association areas.
在这项研究中，我们分析了 20 名健康个体在执行简单注意力任务时诱导的皮质振荡的地形。我们有兴趣在定性上复制我们最近在视觉任务中关于注意力诱导β波段定位的发现[1]，并验证注意力向听觉模式的变化是否会导致显著的地形变化。我们计算了每个诱导频率带的校正潜伏期平均值，并通过最小化 Lp 范数的电流密度重建来模拟它们的发生器。我们通过相关性分析来量化条件之间的地形相似性，而在每个个体案例中则说明了注意力相关的相关性在模态之间的显著性差异。我们复制了注意力相关活动的个体高度独特的地形的定性结果，这在β波段以及之前研究的慢电位分布[2]中都表现出来。头皮电位和皮质电流分布的视觉检查表明，与已知是感官相关电位主要贡献者的θ和δ波段相比，注意力相关波段的变化很小。定量结果与视觉检查一致，支持这样的结论，即注意力相关的活动在模态之间变化不大，而且无论发生何种个体变化，它们在跨个体的皮质定位中都不是系统性的。我们结合其他呈现个体数据的研究的结果，讨论了我们的结果，这些研究的结果与皮质联合区的功能有关。
