Dorobanţu Maria, Tîrziu Cristina, Ghiorghe S, Găinoiu Elena, Zamfir Diana
Department of Cardiology, Floreasca Emergency Hospital, Bucharest, Romania.
Rom J Intern Med. 2009;47(4):363-9.
Peripheral arterial disease (PAD) represents a disease with high prevalence and related mortality and morbidity. However, there are spearing epidemiological information regarding PAD in Romania. The objective of our study was to evaluate the prevalence of PAD in relationship with cardiovascular risk factors (RF) in Romania.
In the study we randomly enrolled a number of 796 patients aged over 40 from those persons presenting during a 3 month period at the warding rooms in The Emergency Hospital in Bucharest. For every patient a questionnaire was completed containing demographical data, information about personal RF and history of atherothrombotic cardio-vascular disease and also information about patient's treatment. For each patient the height, the weight, waist circumference and ankle-brachial index (ABI) have been measured.
The prevalence of PAD was 18.7%, 79.19% from patients being newly diagnosed. Multivascular atherothrombotic disease was noted in 16.1% of PAD patients. FR related with the presence of PAD were age, diabetes mellitus (DM), smoking and former coronary disease. Smoking and DM represented the most unfavourable risk factors association in respect with PAD.
We found a high prevalence of PAD but comparable with that one reported in other European countries. The majority of the patients were newly diagnosed. The RF most frequented encountered have been DM and smoking, their association conducing to further increase in risk of having PAD. We appreciate the necessity of active identification of PAD by means of ABI measurement in patients with RF or other cardiovascular disease.
外周动脉疾病(PAD)是一种患病率高且伴有相关死亡率和发病率的疾病。然而,罗马尼亚关于PAD的流行病学信息匮乏。我们研究的目的是评估罗马尼亚PAD的患病率及其与心血管危险因素(RF)的关系。
在本研究中,我们从布加勒斯特急诊医院病房3个月期间就诊的人群中随机招募了796名40岁以上的患者。为每位患者填写一份问卷,内容包括人口统计学数据、个人RF信息、动脉粥样硬化性心血管疾病史以及患者的治疗信息。测量了每位患者的身高、体重、腰围和踝臂指数(ABI)。
PAD的患病率为18.7%,其中79.19%为新诊断患者。16.1%的PAD患者存在多血管动脉粥样硬化性疾病。与PAD存在相关的RF包括年龄、糖尿病(DM)、吸烟和既往冠心病。吸烟和DM是与PAD相关的最不利的危险因素组合。
我们发现PAD的患病率较高,但与其他欧洲国家报道的患病率相当。大多数患者为新诊断病例。最常遇到的RF是DM和吸烟,它们的组合导致患PAD的风险进一步增加。我们认识到有必要通过测量ABI对有RF或其他心血管疾病的患者进行PAD的主动筛查。