Director, Inflammatory Bowel Disease Clinic, Assistant Professor of Medicine, University of Calgary, Rm. 6D32, TRW Building, 3280 Hospital Drive NW, Calgary, Alberta T2N 4N1.
Therap Adv Gastroenterol. 2010 May;3(3):179-89. doi: 10.1177/1756283X09357579.
Crohn's disease (CD) is a chronic relapsing and remitting disorder of the gastrointestinal tract with no known cure. The inflammation that drives the disease can lead to debilitating symptoms and a number of complications that may lead to surgery. The introduction of biologic therapy a decade ago has offered a new option for patients failing conventional therapy. Over time, biologic therapy has also led to the desire to achieve treatment goals beyond the control of symptoms. In order to achieve short-term and long-term goals with these new agents, it is important to review how these therapies may be optimized for the best results.
克罗恩病（CD）是一种慢性复发性胃肠道疾病，目前尚无治愈方法。导致疾病的炎症可导致衰弱的症状和许多并发症，可能导致手术。十年前生物治疗的引入为传统治疗失败的患者提供了新的选择。随着时间的推移，生物治疗也促使人们希望实现超越症状控制的治疗目标。为了通过这些新药物实现短期和长期目标，重要的是要回顾如何优化这些治疗以获得最佳效果。
