亚铵叶立德在糖酸酰胺的非对映选择性合成中的应用。
Ammonium ylides for the diastereoselective synthesis of glycidic amides.
机构信息
Institute of Organic Chemistry, Johannes Kepler University Linz, Altenbergerstraße 69, 4040 Linz, Austria.
出版信息
Chem Commun (Camb). 2011 Feb 21;47(7):2170-2. doi: 10.1039/c0cc04821f. Epub 2010 Dec 21.
Abstract
A highly trans-selective protocol for the synthesis of glycidic amides was developed. This approach gave access to oxiranes by reacting stabilised ammonium ylides bearing an α-carbonyl group and aromatic aldehydes in moderate to good yields.
摘要
开发了一种高反式选择性合成缩水甘油酰胺的方法。该方法通过反应稳定的带有α-羰基的铵叶立德和芳香醛，以中等至良好的收率得到环氧化物。
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