Paes-Barbosa Fábio Colagrossi, Ferreira Fabio Gonçalves, Szutan Luiz Arnaldo
Serviço de Transplante de Fígado, Santa Casa de Misericordia de São Paulo, São Paulo, SP, Brazil.
Rev Col Bras Cir. 2010 Oct;37(5):370-5. doi: 10.1590/s0100-69912010000500011.
Hepatectomy can comprise excision of peripheral tumors as well as major surgeries like trisegmentectomies or central resections. Patients can be healthy, have localized liver disease or possess a cirrhotic liver with high operative risk. The preoperative evaluation of the risk of postoperative liver failure is critical in determining the appropriate surgical procedure. The nature of liver disease, its severity and the operation to be performed should be considered for correct preparation. Liver resection should be evaluated in relation to residual parenchyma, especially in cirrhotic patients, subjects with portal hypertension and when large resections are needed. The surgeon should assess the rationale for the use of hepatic volumetry. Child-Pugh, MELD and retention of indocyanine green are measures for assessing liver function that can be used prior to hepatectomy. Extreme care should be taken regarding the possibility of infectious complications with high morbidity and mortality in the postoperative period. Several centers are developing liver surgery in the world, reducing the number of complications. The development of surgical technique, anesthesia, infectious diseases, oncology, intensive care, possible resection in patients deemed inoperable in the past, will deliver improved results in the future.
肝切除术可包括外周肿瘤切除以及诸如三段切除术或中央切除术等大型手术。患者可能身体健康、患有局限性肝脏疾病或患有手术风险高的肝硬化肝脏。术前评估术后肝衰竭风险对于确定合适的手术方式至关重要。为了正确准备,应考虑肝脏疾病的性质、其严重程度以及拟实施的手术。肝切除应根据残余实质进行评估,尤其是在肝硬化患者、门静脉高压患者以及需要进行大范围切除的情况下。外科医生应评估使用肝脏体积测量法的依据。Child-Pugh评分、终末期肝病模型(MELD)以及吲哚菁绿潴留是可在肝切除术前用于评估肝功能的指标。对于术后具有高发病率和死亡率的感染性并发症的可能性应格外小心。世界上有几个中心正在开展肝脏手术,减少并发症的数量。手术技术、麻醉、传染病、肿瘤学、重症监护的发展,以及过去被认为无法手术的患者现在可能进行切除,未来将带来更好的结果。