Fundação Santa Casa de Misericórdia, Belém, PA, Brazil.
Núcleo de Medicina Tropical, Universidade Federal do Pará, Belém, PA, Brazil.
PLoS One. 2020 Mar 5;15(3):e0229525. doi: 10.1371/journal.pone.0229525. eCollection 2020.
Determination of hepatic volume is an important preoperative procedure and is done through imaging exams or standard liver volume (SLV) formulas developed based on the biotype of each population. In the absence of a specific SLV formula for the Brazilian Eastern Amazon population, the measurement of liver volume is made with reference values from other populations. The aim of study was to compare the hepatic volume in healthy residents from the Brazilian Eastern Amazon population obtained with magnetic resonance imaging (MRI) and recommended SLV formulas validated to other populations. This was a Observational, cross-sectional study. Anthropometric data of 42 healthy individuals aged 18-60 years of both sexes was collected to measure the liver volume through SLV formulas calculations and MRI. MRI shows similarity with the Western European SLV liver volume values and significant differences with the Japan SLV formula, mainly for women, with a moderate-to-weak correlation with the MRI measurements. There was a strong correlation between weight and body surface area in male patients analysed with measurements of the liver volume by the MRI and SLV formulas. The SLV formula based on the Western European population could be used in the absence of a specific formula for individuals living in the Amazon region. The results suggest that liver measurement formulas should take into consideration the sex of individuals, as well as the development of a specific SLV formula for the Eastern Amazon population and the conduction of similar studies in other Brazilian regions.
肝体积的测定是术前的重要程序,可通过影像学检查或基于各人群生物型的标准肝体积 (SLV) 公式来完成。由于缺乏针对巴西亚马逊东部人群的特定 SLV 公式,因此肝体积的测量是参考其他人群的参考值进行的。本研究的目的是比较通过磁共振成像 (MRI) 获得的巴西亚马逊东部人群健康居民的肝体积,以及与其他人群验证的推荐 SLV 公式。这是一项观察性的、横断面研究。收集了 42 名年龄在 18-60 岁之间的健康个体的人体测量数据,以通过 SLV 公式计算和 MRI 来测量肝体积。MRI 显示与西欧的 SLV 肝体积值相似,与日本的 SLV 公式存在显著差异,主要是针对女性,与 MRI 测量具有中等至弱的相关性。在分析男性患者的肝体积时,体重和体表面积之间存在很强的相关性,通过 MRI 和 SLV 公式进行测量。在缺乏针对居住在亚马逊地区个体的特定公式的情况下,可以使用基于西欧人群的 SLV 公式。研究结果表明,肝测量公式应考虑个体的性别,以及为亚马逊东部人群制定特定的 SLV 公式,并在其他巴西地区进行类似的研究。