[多药联合疗法治愈后出院患者的麻风反应]
[Leprosy reactions in discharged patients following cure by multidrug therapy].
作者信息
Souza Linton Wallis Figueiredo
机构信息
Programa de Pós-Graduação de Ciências da Saúde, Hospital Universitário Clemente Faria, Universidade Estadual de Montes Claros, Montes Claros, MG.
出版信息
Rev Soc Bras Med Trop. 2010 Nov-Dec;43(6):737-9. doi: 10.1590/s0037-86822010000600029.
INTRODUCTION
Reactional states are the main cause of nerve lesions and incapacities provoked by leprosy.
METHODS
Retrospective study aimed at verifying the frequency of leprosy reactions in discharged patients following cure by multidrug therapy (MDT).
RESULTS
Among patients who presented reactions during treatment, 35.5% continued after MDT; of those that did not present during treatment, only 12.7% presented after discharge; 63.4% multibacillary patients presented during and 31.7% after; 27.7% paucibacillary patients presented during and 8.3% after.
CONCLUSIONS
A direct proportional relation exists between the presence of reactions during and after treatment. Multibacillary clinical forms present a greater frequency of reactions during and after cure.
引言
反应状态是麻风病引发神经病变和致残的主要原因。
方法
一项回顾性研究，旨在核实多药联合化疗（MDT）治愈后出院患者中麻风反应的发生频率。
结果
在治疗期间出现反应的患者中，35.5%在MDT后仍有反应；治疗期间未出现反应的患者中，仅12.7%在出院后出现反应；63.4%的多菌型患者在治疗期间出现反应，31.7%在出院后出现反应；27.7%的少菌型患者在治疗期间出现反应，8.3%在出院后出现反应。
结论
治疗期间和治疗后反应的出现呈正比关系。多菌型临床类型在治愈期间和治愈后出现反应的频率更高。
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