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有证据表明结核分枝杆菌的蛋白质抗原b参与磷代谢。

Evidence that protein antigen b of Mycobacterium tuberculosis is involved in phosphate metabolism.

作者信息

Andersen A B, Ljungqvist L, Olsen M

机构信息

Mycobacteria Department, Statens Seruminstitut, Copenhagen, Denmark.

出版信息

J Gen Microbiol. 1990 Mar;136(3):477-80. doi: 10.1099/00221287-136-3-477.

DOI:10.1099/00221287-136-3-477
PMID:2118164
Abstract

Protein antigen b (Pab) of Mycobacterium tuberculosis has previously attracted interest because of its immunological and diagnostic relevance. In this study we present evidence that Pab possesses a signal sequence and is secreted from the cytoplasm of M. tuberculosis. The synthesis of Pab is enhanced under phosphate starvation indicating that the protein is involved in phosphate metabolism in M. tuberculosis.

摘要

结核分枝杆菌的蛋白抗原b（Pab）此前因其免疫学和诊断学相关性而备受关注。在本研究中，我们提供证据表明Pab具有信号序列，并从结核分枝杆菌的细胞质中分泌出来。在磷酸盐饥饿条件下，Pab的合成增强，这表明该蛋白参与了结核分枝杆菌的磷酸盐代谢。

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