Department of Imaging Sciences, University of Rochester, Rochester, New York, USA.
J Magn Reson Imaging. 2011 Jan;33(1):245-51. doi: 10.1002/jmri.22427.
To study the use of an interleaved water-fat (IWF) sequence with a custom-made radiofrequency (RF) coil for high-resolution imaging of arthritic finger joints.
High-resolution finger magnetic resonance imaging (MRI) was performed using a custom-made dedicated RF receiver coil and an IWF sequence. A phantom, a cadaver finger specimen, and the fingers of two normal controls and six arthritic subjects were imaged with a resolution of 156 × 156 × 600 μm. The appearance of anatomic structures on the IWF images were compared with images acquired with a regular sequence. The images were reviewed by two musculoskeletal radiologists for the depiction of anatomical structures and for the presence of abnormalities.
The high-resolution images revealed detailed structures of the finger joints not detectable using typical clinical resolution. The IWF sequence gave more realistic depiction of subchondral bone thickness, and avoided false bone erosions displayed in the regular sequence. It also allowed better visualization of ligaments and tendons.
This pilot study shows the feasibility and the potential usefulness of high-resolution IWF imaging for finger joint evaluation. This technique may be useful for the diagnosis and treatment assessment of arthritis, and for the study of joint disease pathogenesis.
研究使用交错水脂（IWF）序列和定制射频（RF）线圈进行高分辨率成像关节炎手指关节。
使用定制的专用 RF 接收器线圈和 IWF 序列进行高分辨率手指磁共振成像（MRI）。对一个体模、一个手指标本、两个正常对照者和六个关节炎患者的手指进行成像，分辨率为 156×156×600μm。比较 IWF 图像上的解剖结构与常规序列采集的图像。两名肌肉骨骼放射科医生对图像进行了回顾，以评估解剖结构的显示和异常情况的存在。
高分辨率图像显示了使用典型临床分辨率无法检测到的手指关节的详细结构。IWF 序列更真实地描绘了软骨下骨厚度，并避免了常规序列中显示的假骨侵蚀。它还可以更好地显示韧带和肌腱。
这项初步研究表明，高分辨率 IWF 成像用于手指关节评估具有可行性和潜在的有用性。这种技术可能对关节炎的诊断和治疗评估以及关节疾病发病机制的研究有用。
